Abstract:In this study, we determined the plasma TGF-β1 levels in healthy and thrombocytopenic and nonthrombocytopenic neonates who had perinatal risk factors and examined the association between plasma TGF-β1 levels and platelet counts in these newborns to investigate the role of TGF-β1 in the pathogenesis of neonatal thrombocytopenia. Three groups were defined in this prospective study: group 1, thrombocytopenic neonates (n = 22) who had perinatal risk factors; group 2, nonthrombocyto… Show more
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