Plasma vitamin, β-carotene, and α-tocopherol status according to age and disease in hospitalized elderly

Tebi, A.; Belbraouet, Slimane; Chau, Nearkasèn; Debry, G

doi:10.1016/s0271-5317(00)80021-4

Cited by 10 publications

(4 citation statements)

References 68 publications

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“…Hoorn et al, (1975) indicated that mean EAST-AC level was 1.58 AE 0.14 in 153 geriatric patients, which is considered to be adequate. Tébi et al (2000) reported that 590 diseased elderly people had an adequate mean EAST-AC level (1.75 AE 0.38). However, studies (Lui et al, 1985;Ribaya-Mercado et al, 1991) indicated that EAST-AC could be normal in the presence of chronic and marginal vitamin B6 deficiency.…”

Section: Discussionmentioning

confidence: 99%

Vitamin B6 intakes and status of mechanically ventilated critically ill patients in Taiwan

Huang¹,

Ph²,

Chen³

et al. 2002

Eur J Clin Nutr

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Objective: To assess vitamin B6 intake and status of critically ill patients. The relationship between vitamin B6 status indicators and the severity of illness and outcome in these patients was also examined. Design: Prospective clinical study. Setting: The study was performed at the Taichung Veteran General Hospital, in the central part of Taiwan. Subjects: Ninety-four patients in the intensive care unit (ICU) entered the study and 46 patients successfully completed this study. Interventions: No intervention. Main outcome measures: Vitamin B6 intake was recorded for 14 days. Vitamin B6 status was assessed by direct measures (plasma pyridoxal 5 0 -phosphate (PLP), pyridoxal (PL), and urinary 4-pyridoxic acid (4-PA)) and indirect measures (erythrocyte alanine (EALT-AC) and aspartate (EAST-AC) aminotransaminase activity coefficient). The severity of illness (APACHE II score), the length of ventilation dependency, and the length of ICU and hospital stay were recorded. Results: Patients had an adequate mean vitamin B6 intake (16.26 AE 19.39 mg) during the 14 day study. Mean vitamin B6 intake was significantly higher on day 14 than on day 1 (P < 0.001). However, plasma PLP and PL concentrations significantly decreased at the 14th day after admission (P < 0.05). Erythrocyte alanine aminotransaminase activity coefficient and EAST-AC did not change significantly. Urinary 4-PA significantly increased at the 14th day (P < 0.001). No significant relationships were found between APACHE II scores and clinical outcomes (the length of ICU and hospital stay, the length of ventilation dependency) of patients, vitamin B6 intake or status indicators. Conclusions: Critically ill patients received nutritional support in the ICU, and had sufficient mean vitamin B6 intake and adequate vitamin B6 status. Therefore, the severity of illness and the results should not be affected by vitamin B6 status. However, we have noted that plasma PLP and PL concentrations significantly decreased while vitamin B6 intake significantly increased on day 14. Critical clinical conditions and complex metabolism in the critically ill may account for the reduction of plasma PLP and PL. Since vitamin B6 deficiency causes profound effects on immune system function, dietary or supplemented vitamin B6 intake is suggested for hospitalized patients.

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Section: Discussionmentioning

confidence: 99%

Vitamin B6 intakes and status of mechanically ventilated critically ill patients in Taiwan

Huang¹,

Ph²,

Chen³

et al. 2002

Eur J Clin Nutr

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“…Older people are likely to have had the same GP for a longer time, and to consult him or her more often because of their health status. They are more likely to be affected by disability and malnutrition, and are particularly prone to polypathology and to needing ongoing treatment [ 27 , 28 ]. It should be noted that our study highlighted a lower level of TCom-skill GP and perceived adherence among younger age groups.…”

Section: Discussionmentioning

confidence: 99%

How patients perceive the therapeutic communications skills of their general practitioners, and how that perception affects adherence: use of the TCom-skill GP scale in a specific geographical area

Baumann

Baumann²,

Bihan

et al. 2008

BMC Health Serv Res

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“…Traber et al suggested that α-TOH plasma concentrations are more dependent on control mechanisms for plasma lipids rather than on α-TOH absorption [113]. Hospitalized elderly patients [114] as well as older persons with cognitive impairments (dementia or Alzheimer's disease [115,116]) have low α-TOH plasma concentrations [117]. However, an unfavorable nutrient status of the hospitalized patients was discussed as the cause of the lower α-TOH plasma concentrations.…”

Section: Agingmentioning

confidence: 99%

The Hepatic Fate of Vitamin E

Schmölz¹,

Schubert²,

Kluge³

et al. 2018

Vitamin E in Health and Disease

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Vitamin E is a lipophilic vitamin and thus is naturally occurring mainly in high-fat plant products such as oils, nuts, germs, seeds, and in lower amounts in vegetables and some fruits. The term "vitamin E" comprises different structures that are classified as tocopherols, tocotrienols, and "vitamin E-related structures." Vitamin E follows the same route in the body like other lipophilic substances. In brief, vitamin E is absorbed in the intestine, packaged into chylomicrons together with other lipophilic molecules, and distributed via lymph and blood in the body. As the liver is the central organ in lipoprotein metabolism, it is also essential for the uptake, distribution, metabolism, and storage of vitamin E. Based on the current knowledge on that field, the physiological, nonphysiological, and pathophysiological factors influencing the hepatic handling of vitamin E, verifying the crucial role of the liver in vitamin E homeostasis, are described.

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Plasma vitamin, β-carotene, and α-tocopherol status according to age and disease in hospitalized elderly

Cited by 10 publications

References 68 publications

Vitamin B6 intakes and status of mechanically ventilated critically ill patients in Taiwan

Vitamin B6 intakes and status of mechanically ventilated critically ill patients in Taiwan

How patients perceive the therapeutic communications skills of their general practitioners, and how that perception affects adherence: use of the TCom-skill GP scale in a specific geographical area

The Hepatic Fate of Vitamin E

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