Plasmacytoid leukemia in seawater reared Chinook salmon Oncorhynchus tshawytscha

Kent, Michael L.; Groff, J. M.; Traxler, G. S.; Zinkl, Joseph G.; Bagshaw, Joseph C.

doi:10.3354/dao008199

Cited by 45 publications

(32 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In 'Addressee for correspondence; E-mail: rphedrick@ucdavis.ed~l adult and juvenile chinook, E, salrnonis infection is characterized by anemia and a chronic, severe lymphoblastosis with features of leukemia. The pathological features of the disease are similar to those of a plasmacytoid leukemia of possible viral origin that has been reported in seawater-reared chinook from British Columbia (Kent et al 1990, Eaton & Kent 1992, Eaton et al 1994.…”

Section: Introductionsupporting

confidence: 57%

“…Enterocytozoon salmonis is an intranuclear microsporidian parasite of salmonids that has been associated with losses in chinook salmon Oncorhynchus tshawytscha in California, Washington, Oregon, and Idaho in the USA (Elston et al 1987, Hedrick et al 1990, Morrison et al 1990, MacConnell et al 1991 and in British Columbia, Canada (Kent et al 1990). …”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Nested polymerase chain reaction for detection of Enterocytozoon salmonis genomic DNA in chinook salmon Oncorhynchus tshawytscha

et al. 1995

View full text Add to dashboard Cite

A nested polymerase chain reaction (PCR) was developed for detection of the microsporidian parasite Enterocytozoon saln~onis in blolog~cal samples (blood buffy-coat cells, feces, tissues, lymphocyte cultures) of chinook salmon Oncorhynchus tshaulj/tscha. A major second-round PCR product of 407 bp was readily identifiable in ethidium bromide-stained agarose minigels An internal probe was used to verify the identity of the amplified product by non-radioactive (digoxigeninbased) Southern blotting; final confirmation was made by DNA sequence analys~s. A dilution study using infected lymphocytes from in vitro cultures indicated that a single round of PCR (35 cycles) was able to detect E. salrnonis DNA from approximately 1000 infected cells. Sensitivity was increased with the full nested PCR (35 additional cycles), which detected parasite DNA from 110 infected lymphocytes. The specificity of the PCR was assessed with a panel of microsporidian and myxosporean DNAs. In an experimental infection study, E. salmonis DNA was detected in blood, feces, and tissues of infected chinook salmon but not in uninfected control fish.

show abstract

Section: Introductionsupporting

confidence: 57%

Section: Introductionmentioning

confidence: 99%

Nested polymerase chain reaction for detection of Enterocytozoon salmonis genomic DNA in chinook salmon Oncorhynchus tshawytscha

et al. 1995

View full text Add to dashboard Cite

show abstract

“…The virion density is between 1.16 and 1.18 g/ml in sucrose, and they have RT activity (White and Fenner, 1986;Doane and Andersen, 1987;Coffin, 1990). Recently some retroviruses have been reported to induce proliferative consitions in salmonid fish (Duncan, 1978;McKnight, 1978;Kent et al, 1990). Eaton and Kent (1992) reported a retrovirus infection in chinook salmon with plas macytoid leukemia (PL).…”

Section: Discussionmentioning

confidence: 99%

A New Virus Isolated from Salmonid Fish.

Yoshimizu

Kondo

et al. 1995

Fish Pathol.

View full text Add to dashboard Cite

“…Based on transmission trials and the demonstration of reverse transcriptase activity, an oncogenic retrovirus was suggested to cause the esocid neoplasm (Papas et al 1976(Papas et al , 1977. Plasmacytoid leukemia has caused mass mortalities in cultured chinook salmon Oncorhynchus tshawytscha and was revealed to be the retroviral etiology (Kent & Dawe 1990, Eaton & Kent 1992, Eaton et al 1993. Moreover, lymphatic neoplasia have been found to occur spontaneously in medaka (= Japanese lullifish) Oryzias latipes (Kubota et al 1982), tilapia Sarotherodon spilurus (Haller & Roberts 1980), grayling Thymallus thymallus (Hoffman et al 1988) and salmonid fishes (Dunbar 1969, McArdle & Roberts 1974, Roald & Hastein 1979, Bernstein 1984, Warr et al 1984, Bruno & Smail 1998.…”

Section: Introductionmentioning

confidence: 99%

Lympholeukemia in madai Pagrus major in Japan

Miyazaki

Asai²,

Kobayashi³

et al. 2000

Dis. Aquat. Org.

View full text Add to dashboard Cite

Lympholeukemia has been occurring to a n epizootic extent with mass mortality in 1 and 2 yr old madai (= Japanese red sea bream) Pagrus major in the winter season (October-May) in the western regions of Japan slnce 1975. Diseased fish displayed severe anemia and markedly increased numbers of neoplastic lymphocytoid and lymphoblastoid cells in the blood. Neoplasbc cells originated in the splenic lymphatic cells and systemically caused severe metastatic lesions in the heart, liver, kidney, digestive tracts, gdls and the lateral musculature. Electron microscopy revealed adeno-like viral particles (78 to 83 nm in diameter) in the nucleus of lymphoblastoid cells which appeared in the early prevalent stage but no viral particles m the lymphocytold cells or plasmacytoid cells, which subsequently increased in number. In this paper, we describe light and electron microscopic features of neoplasms and neoplastic cells.

show abstract

Plasmacytoid leukemia in seawater reared Chinook salmon Oncorhynchus tshawytscha

Cited by 45 publications

References 8 publications

Nested polymerase chain reaction for detection of Enterocytozoon salmonis genomic DNA in chinook salmon Oncorhynchus tshawytscha

Nested polymerase chain reaction for detection of Enterocytozoon salmonis genomic DNA in chinook salmon Oncorhynchus tshawytscha

A New Virus Isolated from Salmonid Fish.

Lympholeukemia in madai Pagrus major in Japan

Contact Info

Product

Resources

About