Plasmacytoma of the Cervical Spine: A Case Study

Abstract

Objective: The purpose of this case study is to describe the presentation of a patient with plasmacytoma. Clinical Features: A 49-year-old man presented with progressive neck pain, stiffness, and dysphagia to a chiropractic office. A radiograph indicated a plasmacytoma at C3 vertebral body. The lesion was expansile and caused a mass effect anteriorly on the esophagus and posteriorly on the spinal cord. Neurologic compromise was noted with fasciculations and hypesthesia in the right forearm. The patient was referred to a neurosurgeon. Intervention and Outcome: Surgical resection of the tumor was performed with a vertebral body spacer and surrounding titanium cage. Bony fusion was initiated by inserting bone grafts from the iliac crests into the titanium cage. Additional laboratory analysis and advanced imaging confirmed that the plasmacytoma had progressed to multiple myeloma and radiation and chemotherapy were also necessary. Conclusion: A chiropractor recognized a large, expansile plasmacytoma in the C3 vertebral body and referred the patient for surgical care. This case suggests that all practitioners of manual medicine should provide a careful analysis of the patient's clinical presentation and, if clinically warranted, radiographic examination to determine neck or back pain is due to an underlying malignant condition. (J Chiropr Med 2017;16:170-174)

Amiodarone Prevents Atrial Fibrillation Induced by Arsenic Trioxide in Extramedullary Plasmacytoma Involving Lumbar Disc: A Novel Case Report

“…Marrow containing bones especially spine is typical site for SOP. Some recent published cases of spinal plasmacytoma like thoracic (T7-T9), cervical (C3), lumbar (L4) confirm this anatomical region and involvement with malignancy [10][11][12]. In our paper, we described an exceptional case of primary plasmacytoma with lumbar disc involvement.…”

Solitary bone plasmacytoma compression injury disguised as back pain: a case report

“…Several studies have reported the vertebrae to be the most common site of SBP [4,10,13]. Due to lesion compression, back and neck pain are commonly reported initial symptoms of SBP [4], which has been demonstrated by numerous published case reports [14][15][16][17][18][19][20][21][22][23][24][25][26][27]. Of these cases, patients reported pain on average 8 months prior to the diagnosis of SBP.…”

Extramedullary plasmacytoma presenting as a rapidly growing lateral neck mass: A case report

“…Bony collapse, and cord compression can result in significant neurologic compromise. Awareness of the symptoms of presentation: pain, progressive motor and sensory deficits, and myelopathy enhances the ability to make an early diagnosis and intervene surgically before catastrophic neurologic consequences occur [15]. Surgical techniques can vary based on the anatomic location and extent of local destruction caused by the neoplasm.…”