Plasmocitoma extramedular de laringe. A propósito de un caso

Guijarro, Isabel González; González, Laura Díez; Acevedo, Nieves Rodriguez; Pallas, Estrella Pallas

doi:10.1016/j.otorri.2010.04.001

Cited by 6 publications

(3 citation statements)

References 7 publications

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“…The median age of presentation is 56–59 years [2]. It occurs predominantly in males, with a ratio of 3 : 1 [3].…”

Section: Introductionmentioning

confidence: 99%

“…The symptoms of the extramedullary plasmacytoma are mainly dysphonia, dysphagia, cough, and dyspnea [2]. The extramedullary plasmacytomas of the larynx are usually submucosal [5].…”

Section: Introductionmentioning

confidence: 99%

“…Extramedullary plasmacytoma is a localized entity usually associated with a long surveillance [2]. Nevertheless in 16% of the cases, the disease can progress to multiple myeloma [4].…”

Section: Introductionmentioning

confidence: 99%

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Extramedullary Plasmacytoma of the Larynx: A Case Report of Subglottic Localization

Ramírez-Anguiano

Lara-Sánchez

Martínez-Baños

et al. 2012

Case Reports in Otolaryngology

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Extramedullary plasmacytoma (EMP) is a rare neoplasm of plasma cells, described in soft tissue outside the bone marrow. EMP of the larynx represents 0.04 to 0.45% of malignant tumors of the larynx. A male of 57 years old presented with hoarseness, dyspnea, and biphasic stridor of 2 months. The indirect laryngoscopy (IL) revealed severe edema of the posterior commissure and a polypoid mass in the right posterior lateral subglottic wall. A biopsy of the subglottic mass was performed by a direct laryngoscopy (DL). The histopathologic diagnosis was EMP CD138+, therefore radiotherapy was given at 54 Gy in 30 sessions. The patient had an adequate postoperative clinical course and a new biopsy was performed having tumor-free margins. All laryngeal lesions should be biopsied prior to treatment to determine an accurate diagnosis to guide a proper management of the condition. Radiation therapy to the EMP is considered the treatment of choice, having local control rates of 80% to 100%. The subglottis is the least accessible area of view and the least frequent location of a laryngeal mass, nevertheless the otolaryngologist should always do a complete and systematic exam of the larynx when a tumor is suspected, to detect diagnoses such as a subglottic plasmacytoma.

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“…The median age of presentation is 56–59 years [2]. It occurs predominantly in males, with a ratio of 3 : 1 [3].…”

Section: Introductionmentioning

confidence: 99%

“…The symptoms of the extramedullary plasmacytoma are mainly dysphonia, dysphagia, cough, and dyspnea [2]. The extramedullary plasmacytomas of the larynx are usually submucosal [5].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Extramedullary Plasmacytoma of the Larynx: A Case Report of Subglottic Localization

Ramírez-Anguiano

Lara-Sánchez

Martínez-Baños

et al. 2012

Case Reports in Otolaryngology

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Expect the Unexpected: Report of a Case of Pediatric Pharyngeal Extraosseous Plasmacytoma with Tumefactive Amyloidosis (“Amyloidoma”) and a Review of the Literature

Tan

et al. 2015

Head and Neck Pathol

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We report a rare case of localized pharyngeal tumefactive amyloidosis caused by extraosseous plasmacytoma in a 12 year-old girl who presented with otalgia, sore throat and blood stained sputum. The tumor was predominantly composed of amyloid with a limited component of well-differentiated neoplastic plasma cells, which were monoclonal (kappa restricted) on light chain in-situ hybridization. The amyloid deposits were positive for kappa immunoglobulin light chain on immunohistochemistry. The patient was treated with a combination of surgery and radiotherapy. Follow-up at 1 year showed no evidence of recurrence or progression.

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