Plasmodium falciparum AMA1 and CSP antigen diversity in parasite isolates from southern Ghana
Kwadwo A. Kusi,
Linda E. Amoah,
Festus Kojo Acquah
et al.
Abstract:IntroductionDiversity in malarial antigens is an immune evasion mechanism that gives malaria parasites an edge over the host. Immune responses against one variant of a polymorphic antigen are usually not fully effective against other variants due to altered epitopes. This study aimed to evaluate diversity in the Plasmodium falciparum antigens apical membrane antigen 1 (PfAMA1) and circumsporozoite protein (PfCSP) from circulating parasites in a malaria-endemic community in southern Ghana and to determine the e… Show more
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