Plasmonic biochips with enhanced stability in harsh environments for the sensitive detection of prostate-specific antigen

Yeh, I-Hsiu; Shi, Hui-Fang; Darius, Evan; Lien, Mei-Chin; Lu, Yin-Cheng; Wang, Congzhou; Liu, Keng-Ku

doi:10.1039/d3tb02303f

J. Mater. Chem. B

2024

DOI: 10.1039/d3tb02303f

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Plasmonic biochips with enhanced stability in harsh environments for the sensitive detection of prostate-specific antigen

I-Hsiu Yeh,

Hui-Fang Shi,

Evan Darius

et al.

Abstract: Hollow and porous plasmonic nanomaterials have been demonstrated for highly-sensitive biosensing applications due to their distinctive optical properties. Immunosensors, which rely on antibody-antigen interactions, are essential constituents of diverse biosensing...

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Biopolymer-Encapsulated Two-Dimensional Cs₂AgBiBr₆ Field-Effect Based Biosensor for Cardiac Troponin I Sensing

Darius,

Lu,

Shi

et al. 2024

ACS Appl. Nano Mater.

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Two-dimensional (2D) layered semiconductors with excellent electrical, optical, physical, and chemical properties have been extensively investigated over the past decade. Beyond graphene and transition metal dichalcogenides (TMDCs), 2D perovskites have also garnered significant research interest owing to their unique optical and electrical properties. Among 2D perovskites, 2D lead-free double perovskites with inherent stability and remarkable electrical performance are promising for electronic applications. Most immunosensors and traditional bioassays require specialized cold chain systems to maintain biorecognition elements. This study presents the preparation of a 2D perovskite-based biosensor and the integration of a biopolymer to fabricate biopolymerpreserved biosensors with enhanced thermal stability for the sensitive detection of cardiac troponin I (cTnI). This sensing device showed remarkable sensing performance for the detection of cardiac troponin I, with a detection limit of 10 pg/mL. Furthermore, this energy-efficient approach maintained the biosensing capability of the 2D perovskite-based biosensor at elevated temperatures.

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Biopolymer-Encapsulated Two-Dimensional Cs₂AgBiBr₆ Field-Effect Based Biosensor for Cardiac Troponin I Sensing

Darius,

Lu,

Shi

et al. 2024

ACS Appl. Nano Mater.

View full text Add to dashboard Cite

show abstract

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Plasmonic biochips with enhanced stability in harsh environments for the sensitive detection of prostate-specific antigen

Abstract: Hollow and porous plasmonic nanomaterials have been demonstrated for highly-sensitive biosensing applications due to their distinctive optical properties. Immunosensors, which rely on antibody-antigen interactions, are essential constituents of diverse biosensing...

Cited by 1 publication

References 25 publications

Biopolymer-Encapsulated Two-Dimensional Cs₂AgBiBr₆ Field-Effect Based Biosensor for Cardiac Troponin I Sensing

Biopolymer-Encapsulated Two-Dimensional Cs₂AgBiBr₆ Field-Effect Based Biosensor for Cardiac Troponin I Sensing

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Plasmonic biochips with enhanced stability in harsh environments for the sensitive detection of prostate-specific antigen

Abstract: Hollow and porous plasmonic nanomaterials have been demonstrated for highly-sensitive biosensing applications due to their distinctive optical properties. Immunosensors, which rely on antibody-antigen interactions, are essential constituents of diverse biosensing...

Cited by 1 publication

References 25 publications

Biopolymer-Encapsulated Two-Dimensional Cs2AgBiBr6 Field-Effect Based Biosensor for Cardiac Troponin I Sensing

Biopolymer-Encapsulated Two-Dimensional Cs2AgBiBr6 Field-Effect Based Biosensor for Cardiac Troponin I Sensing

Contact Info

Product

Resources

About

Biopolymer-Encapsulated Two-Dimensional Cs₂AgBiBr₆ Field-Effect Based Biosensor for Cardiac Troponin I Sensing

Biopolymer-Encapsulated Two-Dimensional Cs₂AgBiBr₆ Field-Effect Based Biosensor for Cardiac Troponin I Sensing