Plasmonic biosensor for the study of blood diseases by analysis of hemoglobin concentration

Abstract

Plasmonic materials and phenomena are widely studied and applied in multiple fields for an extended time. One among the foremost promising applications is within the engineering of biosensor devices, Diseases of the red blood cells are among the diseases of the blood. Anemia as an example is an abnormal reduction within the concentration of hemoglobin within the blood. When the amount of red blood cells decreases, so does the concentration of hemoglobin. The tissues and organs not receive sufficient oxygen to work normally. This numerical study will give a contribution or approach on the behavior of blood with surface plasmons resonance SPR by analyzing the performance of SPR with any changes in hemoglobin concentrations (refractive index) for the application of technique in the detection of blood diseases.

Improve sensitivity for the study of blood diseases by analysis of hemoglobin concentration using a graphene-coated SPR based biosensor

“…They have significant benefits over traditional analytical techniques because they allow for the direct, unlabelled identification of various biological tissues in real time, such as hemoglobin and chemicals. It has good specificity, sensitivity, compact size, and profitability [4]. The most well-known SPR sensor setup is that provided by Kretschmann.…”

Improve sensitivity for the study of blood diseases by analysis of haemoglobin concentration using a graphene-coated SPR based biosensor

“…They have signi cant bene ts over traditional analytical techniques because they allow for the direct, unlabelled identi cation of various biological tissues in real time, such as hemoglobin and chemicals. It has good speci city, sensitivity, compact size, and pro tability [4]. The most well-known SPR sensor setup is that provided by Kretschmann.…”

“…This circumstance necessitates a unique and precise approach for diagnosis of this disorder. The diagnosis of blood pathologies such as anemia based on the detection of hemoglobin levels in blood samples [4]. Hemoglobin is a protein found in red blood cells that is responsible for transporting oxygen [5].…”

Dynamic modeling of photoacoustic sensor data to classify human blood samples

“…In the study of blood, different techniques provide valuable information about its composition, function, and diseases [ 5 – 7 ]. For instance, electrical [ 8 ], magnetic [ 9 ], and optical [ 10 ] techniques have been used to obtain several features of the blood. However, these methods are usually expensive and require prior preparation of the samples to be analyzed.…”