“…3 In 1977, 4 SERS was described as a Raman enhancement phenomenon that occurs on the surface of precious metals. In recent years, SERS has benefited from developments in optics, laser technology, and nano-devices, and has become one of the most widely used spectroscopic techniques, with applications in areas such as molecular identification 5,6 biological sensing, 7-9 environmental analysis, 10,11 and national security. [12][13][14] Compared to other highly efficient techniques, SERS is easy to use, damage-free, and impervious to water (which is present in many samples), which eliminates the need for laborious sample preparation processes.…”