“…SPR-based sensors have been successfully applied in the detection of some volatile compounds and gases like benzene, ammonia, chloroform, ethanol, methanol, ethyl benzene, 2-propanol, toluene, and acetone vapours [8,[26][27][28][29][30][31][32]. The performance of the sensors has been improved through various design modifications which include the incorporation of nanoparticles of different morphologies [33][34][35], bimetallic layers [2,[36][37][38][39], porous gold [40][41][42][43], graphene layer on gold [5,44], conducting and insulating polymer coatings [26,45,46], and metal oxide coatings [47,48]. However, SPR detection of acetone vapour has not been optimized for suitable applicability in diabetes monitoring and screening [32].…”