1984
DOI: 10.1111/j.1600-0609.1984.tb02173.x
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Platelet Cyclo‐Oxygenase Deficiency in a Japanese

Abstract: A case of platelet cyclo‐oxygenase deficiency in a Japanese was investigated. There was a marked decrease of aggregation with collagen and absence of aggregation with epinephrine and arachidonic acid. The platelet response to a labile aggregation stimulating substance (LASS) was normal. There was no biosynthesis of prostaglandin endoperoxides from arachidonate. The platelets, including granular volume, showed no ultrastructural abnormalities. The responses to various inducers of platelet aggregation, except fo… Show more

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Cited by 10 publications
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