Platelet-derived extracellular vesicles ameliorate intervertebral disc degeneration by alleviating mitochondrial dysfunction

Progress of cell membrane-derived biomimetic nanovesicles for cancer phototherapy

“…Drug delivery technologies have reduced side effects while enhancing biocompatibility, pharmacokinetics, and therapeutic efficacy. 140,141 Due to their comparable homing characteristics or self-expressed signal molecules, biomimetic nanoparticles are very effective at targeting tumors. 142,143 Similarly, because of their inherent existence in vivo, good biocompatibility and lengthy circulation times are simultaneously achieved.…”

Camptothecin-based prodrug nanomedicines for cancer therapy

“…Firstly, cells take up external materials via endocytosis to form a vesicle around them. 145 Then a lysosome can be fused to break them down with its hydrolytic enzymes inside the acidic environment (around 4.0–5.0 pH value). 146,147 Since the pH of the tumor microenvironment varies dramatically from normal tissue, rationally designed pH-responsive nanoparticles can selectively release therapeutic drugs, such as CPT, into tumor sites for enhanced tumor therapy.…”

CHN nanocomposites and nanocoating resist enamel white spot lesions by enhancing remineralization and antibacterial activity

“…Nowadays, a series of novel calcium phosphate-based remineralization delivery systems have been developed for clinical remineralization. 26–28 However, different forms of calcium phosphate have different stability and solubility in the oral environment, and require controlled release through specific carriers. 25,29,30 Therefore, designing a sustained release system is helpful for calcium phosphate to play a better remineralization role.…”