Platelet Rich Plasma Injection for Soft Tissue Musculoskeletal Pain

Irianto, Komang Agung; Ah, Bakri; Kloping, Nabila Ananda

doi:10.5704/moj.2107.014

Cited by 2 publications

(2 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…At four weeks after the intervention, the mean VAS score decreased from 6.8 ± 1.2 (the baseline) to 3.2 ± 1.5, and at eight weeks, it decreased to 2.1 ± 1.0. These findings are consistent with previous studies that have demonstrated the potential analgesic effects of PRP in various musculoskeletal conditions [13][14][15]. The proposed mechanism involves the release of platelet growth factors, modulating inflammation, and promoting tissue repair [16].…”

Section: Discussionsupporting

confidence: 92%

Platelet-Rich Plasma in the Management of Temporomandibular Joint Pain in Young Adults With Temporomandibular Disorder

Mathpati,

Jain,

Mishra

et al. 2024

Cureus

View full text Add to dashboard Cite

Background: Temporomandibular disorder (TMD) encompasses a range of conditions affecting the temporomandibular joint (TMJ) and associated structures, with TMJ pain being a prevalent symptom. Conventional management strategies have limitations, which require the exploration of innovative interventions. Platelet-rich plasma (PRP), known for its regenerative properties, presents a potential therapeutic avenue. This study aims to investigate the effectiveness of PRP in reducing the pain associated with mild TMJ in young adults.Methodology: Participants (n = 128) aged 18 to 35 years with mild TMD were evenly randomized into PRP treatment and placebo control groups. PRP was prepared using a standardized protocol, and intra-articular injections were administered. Placebo injections mimic PRP. Follow-up evaluations were carried out at four and eight weeks after the intervention.Results: The study successfully randomized comparable groups, and the PRP treatment group experienced a significant reduction in TMJ pain (visual analog scale [VAS] score: 6.8 ± 1.2 to 2.1 ± 1.0 at eight weeks, P < 0.001). The PRP treatment also increased the largest opening of the mouth (from 38.2 ± 2.5 to 43.5 ± 3.1, P < 0.001) and the number of lateral movements (12.3 ± 1.5 to 14.9 ± 2.0, P < 0.001), while the placebo group had very few changes. Positive patient-reported outcomes on daily activities were observed, with no serious complications reported in either group.Conclusions: This study provides evidence supporting the efficacy of PRP in reducing TMJ pain, improving jaw function, and improving quality of life in young adults with mild TMD. The results underscore the potential of PRP as a minimally invasive intervention for TMJ disorders.

show abstract

Section: Discussionsupporting

confidence: 92%

Platelet-Rich Plasma in the Management of Temporomandibular Joint Pain in Young Adults With Temporomandibular Disorder

Mathpati,

Jain,

Mishra

et al. 2024

Cureus

View full text Add to dashboard Cite

show abstract

“…While promising, PRP is invasive and time-consuming. PRP requires the injured person to undergo a series of blood withdrawals, platelet enrichment of the blood samples, and reinjection of the fractionated plasma into the injury site [ 22 , 74 , 75 ].…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Sustained Acoustic Medicine for Treating Musculoskeletal Injuries in Military and Sports Medicine

Walters¹,

Kasik²,

Ettel³

et al. 2022

TOORTHJ

View full text Add to dashboard Cite

Background Musculoskeletal injuries are common in collegiate, professional, and military personnel and require expedited recovery to reduce lost worktime. Sustained acoustic medicine (SAM) provides continuous long-duration ultrasound at 3MHz and 132mW/cm2. The treatment is frequently prescribed to treat acute and chronic soft tissue injuries and reduce pain. The objective of this study was to evaluate the efficacy of SAM treatment for musculoskeletal injuries and accelerated recovery. Methods An 18-question electronic survey and panel discussion was conducted on Athletic Trainers (ATs) using SAM treatment in professional, collegiate, and military sports medicine. The survey included both qualitative and quantitative questions. In addition, SAM effectiveness was discussed with expert ATs in a panel discussion. Power calculation of sampling and statistical evaluation of data was utilized for the generalizability of the results. Results Survey respondents (n=97) and panelists (n=142) included ATs from all National Athletic Trainers Association districts. SAM was primarily used for musculoskeletal injuries (83.9%, p<0.001) with a focus on healing tendons and ligaments (87.3%, p<0.001). SAM treatment was also used on joints (44.8%), large muscle groups (43.7%), and bone (41.4%). SAM provided clinical improvement in under 2 weeks (68.9%, p<0.001) and 50% reduction of pain medication (63%, p<0.001). In addition, patients were highly receptive to treatment (87.3%, p<0.001), and ATs had a high level of confidence for improved function and returned to work after 30-days of SAM use (81.2%, p<0.001). Conclusion SAM is an effective, safe, easy to use, noninvasive, comfortable, and versatile therapeutic for healing musculoskeletal injuries.

show abstract

Platelet Rich Plasma Injection for Soft Tissue Musculoskeletal Pain

Cited by 2 publications

References 18 publications

Platelet-Rich Plasma in the Management of Temporomandibular Joint Pain in Young Adults With Temporomandibular Disorder

Platelet-Rich Plasma in the Management of Temporomandibular Joint Pain in Young Adults With Temporomandibular Disorder

Evaluation of Sustained Acoustic Medicine for Treating Musculoskeletal Injuries in Military and Sports Medicine

Contact Info

Product

Resources

About