2012
DOI: 10.1186/ar3914
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Platelet-rich plasma therapy - future or trend?

Abstract: Chronic complex musculoskeletal injuries that are slow to heal pose challenges to physicians and researchers alike. Orthobiologics is a relatively newer science that involves application of naturally found materials from biological sources (for example, cell-based therapies), and offers exciting new possibilities to promote and accelerate bone and soft tissue healing. Platelet-rich plasma (PRP) is an orthobiologic that has recently gained popularity as an adjuvant treatment for musculoskeletal injuries. It is … Show more

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Cited by 236 publications
(225 citation statements)
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“…Although lateral epicondylitis has been the focus of this editorial, PRP therapies have become widely used for a variety of acute and chronic musculoskeletal injuries [11,12,22]. Lengthy recovery times and residual symptoms, combined with patient demand for an expedited return to activities has increased the popularity of PRP dramatically in the past decade.…”
Section: Prp For Other Conditionsmentioning
confidence: 99%
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“…Although lateral epicondylitis has been the focus of this editorial, PRP therapies have become widely used for a variety of acute and chronic musculoskeletal injuries [11,12,22]. Lengthy recovery times and residual symptoms, combined with patient demand for an expedited return to activities has increased the popularity of PRP dramatically in the past decade.…”
Section: Prp For Other Conditionsmentioning
confidence: 99%
“…The rationale behind its use lies in its potential ability to provide growth factors to the relatively avascular diseased tendon, thus promoting tissue healing and tendon regeneration [11]. PRP has gained a significant amount of attention in orthopaedic and sports medicine communities in the past decade, largely due to the promising results of pre-clinical laboratory studies [5,11,12]. In practice, PRP is applied by single or multiple injections to the area of maximal tenderness [5].…”
Section: Introductionmentioning
confidence: 99%
“…In the musculoskeletal field, although no long-term outcome studies with PRP exist, a large number of patients have been treated worldwide [24][25][26][27]. In our review of the literature we did not come across RCT's that have comprehensively evaluated the safety of PRP treatment [10].…”
Section: Spine Research Issn 2471-8173mentioning
confidence: 99%
“…PRP was a major initial step that led researchers to consider bone marrow aspirates and stem cells in the growing field of orthobiologics [10]. The role of PRP in the directed stimulation of musculoskeletal and mesenchymal stem cells is being widely investigated and shows promise as a short-term use agent that may assist in the simultaneous healing of several musculoskeletal tissues with trauma or elective surgery [6,[14][15][16].…”
Section: Spine Research Issn 2471-8173mentioning
confidence: 99%
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