2013
DOI: 10.1134/s1819712413030021
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Platelet serotonin in multiple sclerosis and its relationship with fatigue syndrome

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Cited by 3 publications
(2 citation statements)
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“…Serotonin is a neurotransmitter whose uptake, expression, and transmission is altered in MS (67). Lower levels (≤100 ng/10 9 platelets) of circulating serotonin correspond with fatigue severity score (P = .046) and depression (Beck scale, P = .024) in MS (68). Although the role of serotonin in MS progression is not well understood, it does appear to modulate g-aminobutyric acid-ergic and glutamatergic transmission (69).…”
Section: Imaging Agents Based On Established Therapeutic Drugsmentioning
confidence: 99%
“…Serotonin is a neurotransmitter whose uptake, expression, and transmission is altered in MS (67). Lower levels (≤100 ng/10 9 platelets) of circulating serotonin correspond with fatigue severity score (P = .046) and depression (Beck scale, P = .024) in MS (68). Although the role of serotonin in MS progression is not well understood, it does appear to modulate g-aminobutyric acid-ergic and glutamatergic transmission (69).…”
Section: Imaging Agents Based On Established Therapeutic Drugsmentioning
confidence: 99%
“…Neurobiology and immunology studies indicate that immune system regulation is affected by external factors in the nervous system known as neurotransmitters, including serotonin or 5-hydroxytryptamine (5-HT) [6]. Evidence has shown that fluctuation of serotonin level can be effective in progress of MS [7,8]. Seven families of serotonin receptors (5-HT 1-7 ) have been identified.…”
Section: Introductionmentioning
confidence: 99%