Platelet transfusion in adults: An update

Rapid test for platelet viability relying on a quartz crystal microbalance assay

“…Platelet transfusions are usually carried out at a flow rate of 2-5 mL min −1 or less in patients with the risk of fluid overload. 43 Naturally, observing platelet viability prior to transfusion is more important for patients at risk, which is why a flow rate of 1 mL min −1 was chosen for this experiment measuring only one sensor response per day.…”

Engineering unactivated platelets for targeted drug delivery

“…Among the natural cells, due to good biocompatibility, easy obtainability, long circulation time and accessibility throughout the body, therapeutic blood cells (such as concentrated red blood cells and platelet concentrates) have been successfully used in clinics for many years. 14,15 In addition, the engineering transformation and applications of blood cells have generated various research hotspots, such as drug delivery carriers. Platelets are present in the activated state or unactivated state in vivo.…”

Discussion on the recruitment strategy for apheresis platelet donors in Chongqing during a public health emergency*

“…With the advancing level of medical development in Chongqing and the implementation of universal health insurance policies, clinical component blood transfusions have become increasingly prevalent ( 1 , 2 ). The clinical demand for apheresis platelets has increased accordingly ( 3 , 4 ). However, due to the protracted collection process ( 5 ), specific storage requirements ( 6 ), and short shelf life of apheresis platelets ( 7 ), recruiting donors for this component has become a challenging endeavor, often resulting demand exceeding the available supply ( 8 ).…”