Small unmanned aircraft systems (sUAS) have gained significant popularity with applications ranging from aerial imagery acquisition to package delivery and military surveillance. This popularity is reflected in a variety of startups, the hobbyist community, and in academia. sUAS are employed in academia for both research and teaching purposes. Despite widespread use of sUAS at the university level, most literature focuses on research and commercial applications with few publications dedicated to sUAS for engineering education. This paper investigates the use of sUAS and student-designed manipulator payloads to support both Aerospace and Robotics senior and graduate-level courses developed at the University of Michigan. Four project case studies relying on small unmanned systems will be investigated that collectively provide an integrated learning environment over software, sensor, actuator, and decision-making (control) algorithms. Two of the projects also offer the opportunity for students to design, build, and test a manipulator on a fixed base then integrate it within a quadrotor platform tasked with accomplishing an autonomous manipulation mission. The paper discusses specifics of the projects, project and student learning outcomes, and safety measures applied, including institutional safety policy. Specific outcomes and challenges of course projects are discussed.