Platinum(II) and palladium(II) saccharinato complexes with 2,2′:6′,2″-terpyridine: Synthesis, characterization, crystal structures, photoluminescence and thermal studies

Cell death-inducing effect of novel palladium(II) and platinum(II) complexes on non-small cell lung cancer cells in vitro

“…Therefore, diVerent Pd complexes with promising activity against varying kinds of tumor cell lines have been synthesized and tested over years (Budzisz et al 2004;Abu-Surrah et al 2008;Ruiz et al 2008;Eryazici et al 2008;Divsalar et al 2010;Al-Masoudi et al 2010;Tamasi et al 2010 (Guney et al 2010). Their chemical structures are illustrated in Fig.…”

Palladium(II) saccharinate complexes trans-[Pd(sac)2(LH)2] with amino- and acetylamino-pyridine co-ligands: molecular structures of trans-[PdCl2(2-ampyH)2].2dmf (2-ampyH = 2-amino-3-methylpyridine) and trans-[Pd(κ2-2-acmpy)2] (2-acmpyH = 2-acetylamino-3-methylpyridine)

“…H} NMR spectra were recorded on Varian Unity 500 and Gemini 2000 spectrometers, respectively, with CDCl 3 , d 6 -dmso or d 7 -dmf as solvent and internal reference. IR spectra were recorded on a Shimadzu FT-IR 8400 spectrophotometer in the 400-4,000 cm -1 range using KBr discs and in the 200-600 cm -1 using CsI discs.…”

“…There is continued interest in the chemistry of saccharinate (sac) complexes as co-ligands in biological studies [1,2], and consequently, a number of reports have recently appeared on the synthesis of platinum and palladium saccharinate complexes [3][4][5][6][7][8][9][10][11]. While saccharinate can bind to metal centres in a variety of different ways [1,2] at the relatively soft Pd(II) and Pt(II) centres, it is always N-bound (Fig.…”

“…Continuing our recent studies in this area [12][13][14], we herein provide details of the synthesis of four new palladium saccharinate complexes, trans-[Pd(sac) 2 (LH) 2 ], derived from commercially available or readily prepared amino-or acetylamino-pyridines. Yilmaz and co-workers have also recently detailed the synthesis of related complexes with pyridine and substituted pyridine co-ligands [6][7][8][9][10][11] and have studied their biological properties [16][17][18][19].…”

A comparative study of the coordination of saccharinate (sac), thiosaccharinate (tsac) and benzisothiazolinate (bit) ligands to trans-[PdCl2(H2NBz)2]: molecular structure of cis-[Pd(bit)2(H2NBz)2]

“…1) are versatile poly-functional ligands, shown to adopt a variety of coordination modes, and consequently their coordination chemistry has been widely studied [1,2]. Palladium(II) and platinum(II) complexes of these ligands have been detailed [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18] with some showing promising biological properties [19][20][21][22][23][24]. In contrast, the coordination chemistry of the related benzisothiozolinate (bit) anion ( Fig.…”