Plausible molecular and crystal structures of chitosan/HI type II salt

Lertworasirikul, Amornrat; Noguchi, Keiichi; Ogawa, K.; Okuyama, Kenji

doi:10.1016/j.carres.2004.01.002

Cited by 23 publications

(10 citation statements)

References 25 publications

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“…Two iodide ions are packed between the corner chains, while the two other ions are located between the corner and center chain. One of the intramolecular O3 -O5 hydrogen bonds at glycoside linkage is weakened by interaction with iodide ions, see [12] (Fig. 5a, 5b).…”

Section: Salts and Complexesmentioning

confidence: 97%

Recent Advances in Drugs and Prodrugs Design of Chitosan

Vinšová¹,

Vavříková

2008

CPD

109

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The aim of this review is to outline the recent advances in chitosan molecular modeling, especially its usage as a prodrug or drug in a field of antibacterial, anticarcinogenic and antioxidant activity. Polymeric materials like peptides, polysaccharides and other natural products have recently attracted attention as biodegradabile drug carriers. They can optimize clinical drug application, minimize the undesirable drug properties and improve drug efficiency. They are used for the slow release of effective components as depot forms, to improve membrane permeability, solubility and site-specific targeting. Chitosan is such a prospective cationic polysaccharide which has shown number of functions in many fields, including bio medicinal, pharmaceutical, preservative, microbial and others. This article discusses the structure characteristics of chitosan, a number of factors such as degree of polymerization, level of deacetylation, types of quarternisation, installation of various hydrophilic substituents, metal complexation, and combination with other active agents. Biodegradable, non-toxic and non-allergenic nature of chitosan encourages its potential use as a carrier for drug delivery systems in all above mentioned targets. The use of chitosan prodrug conjugates is aimed at the site-specific transport to the target cells use, for example, a spacer tetrapeptide Gly-Phe-Leu-Gly, promotion of drug incorporation into cells via endocytosis, hybridization or synergism of two types of drugs or a drug with a bioactive carrier. The design of chitosan macromolecule prodrugs is also discussed.

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Section: Salts and Complexesmentioning

confidence: 97%

Recent Advances in Drugs and Prodrugs Design of Chitosan

Vinšová¹,

Vavříková

2008

CPD

109

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“…This is probably due to the structural change of chitosan from a stretched chain into a coiled one, and finally it changes into intertwisted coils or four-fold helix to produce an asymmetric disaccharide unit [21]. This process is expected to be the limiting factor of the crystal growth.…”

Section: Xrd Spectroscopymentioning

confidence: 99%

Photocatalytic Decolorization Study of Methyl Orange by TiO<sub>2</sub>–Chitosan Nanocomposites

Fajriati¹,

Mudasir²,

Wahyuni³

2014

Indones. J. Chem.

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The photocatalytic decolorization of methyl orange (MO) ABSTRAK Telah dilakukan studi reaksi dekolorisasi metil orange (MO) terkatalisis nanokomposit TiO 2 -kitosan. Studi diawali dengan sintesis nanokomposit TiO 2 -kitosan menggunakan metode sol gel dengan variasi konsentrasi titanium (IV) isopropoksida (TTIP) sebagai prekursor. Struktur, morfologi, sifat termal dan optis dikarakterisasi menggunakan X-ray diffraksi (XRD), Fourier transform infra red (FTIR) spektroskopi, scanning electron microscopy (SEM), thermogravimetric analysis (TGA), dan diffuse reflectance ultra violet (DRUV) spektroskopi. Aktivitas fotokatalitik nanokomposit TiO

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“…Comparison of the lines of intensity for the experimental and theoretical spectra showed that the lines in the field of 1500-1700∼ cm -1 are the deformation vibrations of functional groups (NH 2 ) 2 ′, (NH 2 ) 2 and (CH 2 ) 6 , (CH 2 ′) 6 rings of chitosan, lines in the field of 1350-1400∼ cm -1 refer to the external deformation vibrations of ОH, О´H´, СH, С´H´ bonds, lines in the field of 1000-1100∼ cm -1 are the valence vibrations of СО, С´О´. The process of adsorbtion studied in the work demonstrated that the chitosan dimer is better adsorbed on the surface of the bilayer grapheme.…”

Section: Resultsmentioning

confidence: 97%

“…In the paper [5] the atomic structure of the parallel and anti-parallel chitosan strings is studied, and also the Van der Waals distance between these strings is determined. Authors of [6] managed to define the Cartesian coordinates of the chitosan cell atoms using the least-squares method.…”

Section: Introductionmentioning

confidence: 99%

Strain-hardening effect of graphene on a chain of the chitosan for the tissue engineering

et al. 2012

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We report the results of the chitosan dimer study, the mechanism of its interaction with the carbon nanostructures and also the mechanical properties of the chitosan/graphene, chitosan/nanotube complexes using the density function and the molecular dynamic methods. It was established that the physical adsorption of the chitosan with graphene is carried out by the Van der Waals interaction between the hexagonal links of the chitosan with the hexagonal cell of the atomic grid of graphene and nanotube.

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Plausible molecular and crystal structures of chitosan/HI type II salt

Cited by 23 publications

References 25 publications

Recent Advances in Drugs and Prodrugs Design of Chitosan

Recent Advances in Drugs and Prodrugs Design of Chitosan

Photocatalytic Decolorization Study of Methyl Orange by TiO<sub>2</sub>–Chitosan Nanocomposites

Strain-hardening effect of graphene on a chain of the chitosan for the tissue engineering

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