This study critically examines the development of audiovisual and interactive content that draws on Edgar Allan Poe’s oeuvre, with a particular focus on the interplay of transmedia storytelling and gothic elements within these narratives. Utilizing summative content analysis and non-participant observation, this research investigates five films and five independent video games that reinterpret Poe’s literary themes. The results underscore the necessity of incorporating Mythos, Topos, and Ethos in adaptations to faithfully evoke the profound emotional resonance and explore the psychological and existential dilemmas inherent in Poe’s works. Our analysis reveals distinct narrative strategies in cinema and video games: while horror predominates in film, integrating supernatural elements to evoke fear, video games predominantly leverage noir, crafting complex crime narratives infused with cynicism and dark ambiance. Additionally, the study highlights how gothic elements of abjection and sublimity are leveraged to navigate themes of mortality, morality, and the uncanny, thereby ensuring the continued relevance of Poe’s legacy in contemporary media landscapes. This adaptation process not only preserves the essence of Poe’s narrative but also dynamically engages a modern audience through innovative transmedia platforms, illustrating the enduring impact of his work on popular culture.