Pleomorphic Adenoma of the Middle Ear and Mastoid With Posterior Fossa Extension

Peters, Brian R.; Maddox, H. Edward; Batsakis, John G.

doi:10.1001/archotol.1988.01860180090038

Cited by 25 publications

(15 citation statements)

References 10 publications

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“…Salivary gland tumors account for less than 7% of neoplasms involving the head and neck region [4]. These tumors are also reported in various other sites including the skin, neck, thyroid gland, mastoid bone, middle ear, and jawbones [5][6][7][8][9].…”

Section: Introductionmentioning

confidence: 99%

Clear Cell Entities of the Head and Neck: A Selective Review of Clear Cell Tumors of the Salivary Glands

Said-Al-Naief

Klein

2008

Head and Neck Pathol

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Clear cell changes may be observed in virtually any benign or malignant tumor of epithelial, mesenchymal, melanocytic and hematopoeitic derivation not be attributed to variable etiologies. In general, benign and malignant clear cell neoplasms of the head and neck are rare. They may involve various regions and may be of diverse derivations, with only 1-2% of tumors of the salivary glands, jaws and oral mucosa are primarily or almost exclusively composed of clear cells (Maiorano et al., Semin Diagn Pathol 14:203-212, 1997). This review will selectively discuss the clinicopathological features of salivary gland tumors with clear cell changes, which, at times, may pose a diagnostic challenge and dilemma.

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Section: Introductionmentioning

confidence: 99%

Clear Cell Entities of the Head and Neck: A Selective Review of Clear Cell Tumors of the Salivary Glands

Said-Al-Naief

Klein

2008

Head and Neck Pathol

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“…In this case, bone changes were atypical, with a destructive appearance on CT more suggestive of an aggressive lesion. An aggressive pattern of bone destruction has been described in recurrent pleomorphic adenoma following presumed incomplete surgical excision [6] and there are single case reports of bone destruction associated with pleomorphic adenoma of the lacrimal gland [7] and middle ear/mastoid [8]. However, this appearance is unusual and should be considered a feature suggestive of malignancy in routine clinical practice.…”

Section: Discussionmentioning

confidence: 99%

Pleomorphic adenoma of the nasopharyngeal mucosal space with locally aggressive appearance (2010: 11b)

et al. 2011

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Pleomorphic adenoma arising from submucosal minor salivary gland tissue in the head and neck is well described in the published literature. Where associated bone changes are present, benign-appearing bone remodelling is the rule, reflecting the slow growth of this benign tumour. Aggressive-appearing bone destruction was observed in this case. This atypical appearance has not been widely described.

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“…Occasionally, heterotopic salivary tissues may undergo neoplastic transformation [40]. Four cases of these tumors have been reported in this location (table 2) [38,[41][42][43].…”

Section: Reported Cases Of Heterotopic Salivary Tumors In the Middle Earmentioning

confidence: 99%

“…In 1983, Cannon and McLean [42] reported an extensive adenoid cystic carcinoma of the middle ear cleft, which may have arisen from a choristoma of the middle ear. In 1988, Peters et al [43] published a case of primary pleomorphic adenoma of the middle ear and mastoid, with extension into the posterior cranial fossa. The lesion was characterized by extensive bony destruction and close proximity to the facial nerve.…”

Section: Reported Cases Of Heterotopic Salivary Tumors In the Middle Earmentioning

confidence: 99%

Salivary Gland Choristoma of the Middle Ear

Rinaldo

Ferlito

Devaney

2004

ORL

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While head and neck surgeons are accustomed to recognizing malignancies in their practices, developmental lesions are much less often encountered, and as such are not as likely to be included amongst other (more aggressive) differential diagnostic considerations. One such developmental lesion is the choristoma, defined as an architecturally normal arrangement of mature tissues found in a location not normally host to such tissues. Choristomas composed of recognizable salivary gland tissue may be found in a variety of locations including the middle ear. Middle ear salivary choristomas are distinctly unusual lesions and typically manifest as unilateral conductive hearing loss; while both adult and pediatric patients have been diagnosed with middle ear choristomas, most patients have been in the first two decades of life. As these are benign, nonprogressive lesions, treatment has been directed toward complete surgical excision whenever feasible, and biopsy for diagnosis with subsequent observation in the case of those lesions which are difficult to remove without endangering the facial nerve. There have been rare instances in which choristomas have been linked to the subsequent development of neoplasms, but in the main choristomas are regarded as self-limited developmental heterotopias.

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Pleomorphic Adenoma of the Middle Ear and Mastoid With Posterior Fossa Extension

Cited by 25 publications

References 10 publications

Clear Cell Entities of the Head and Neck: A Selective Review of Clear Cell Tumors of the Salivary Glands

Clear Cell Entities of the Head and Neck: A Selective Review of Clear Cell Tumors of the Salivary Glands

Pleomorphic adenoma of the nasopharyngeal mucosal space with locally aggressive appearance (2010: 11b)

Salivary Gland Choristoma of the Middle Ear

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