Pleomorphic Adenoma of the Palate

Abstract

Pleomorphic adenoma, is the most common tumor (50%) of the major and minor salivary glands. Seventy percent of the tumors of the minor salivary glands are pleomorphic adenomas, and the most common intraoral site is the palate, followed by the upper lip and buccal mucosa. Pleomorphic adenoma appears as a painless firm mass and, in most cases, does not cause ulceration of the overlying mucosa. Generally it is mobile, except when it occurs in the hard palate. Intraoral mixed tumors, especially those noted within the palate, lack a well-defined capsule. Lesions of the palate frequently involve periosteum or bone. Approximately 25% of benign mixed tumors undergo malignant transformation. Treatment for the pleomorphic adenoma is radical surgery. Inadequate resection leads to local recurrence. The authors report a palate pleomorphic adenoma in a 67-year-old female patient.

Pleomorphic Adenoma of Hard Palate: An Experience

“…FNAC can also distinguish primary salivary tumor from metastatic disease. Core needle biopsy is more invasive but is more accurate compared to FNAC with diagnostic accuracy greater than 97 % [14] and we found 100 % diagnostic accuracy of core needle biopsy. Furthermore, core needle biopsy allows more accurate histological typing of the tumor.…”

Pleomorphic Adenoma of the Palate

“…Core needle biopsy is more invasive but is more accurate compared to FNA with diagnostic accuracy greater than 97% [3]. Furthermore, core needle biopsy allows more accurate histological typing of the tumor.…”

“…Treatment for the PA is radical surgery. Inadequate resection leads to local recurrence [3]. Accessing Medline, with the key words pleomorphic adenoma, benign tumor of hard palate, pleomorphic adenoma of anterior palate we did not come across any published case report of pleomorphic adenoma of anterior hard palate.…”

Pleomorphic adenoma located in the buccal region

“…Bukkal mukozada enükleasyon, parotis tümörlerinde ise süperfisiyal veya total parotidektomi uygulanmalıdır. [2] Biz olgumuza mevcut kitlesinin kapsülü ile çıkartılmasını sağlayacak bir cerrahi uyguladık.…”

“…Minör tükürük bezi kaynaklı tümörlerin en sık görül-dükleri bölge sert ve yumuşak damaktır, daha sonra sıklık sırasına göre üst dudak ve bukkal mukoza gelmektedir. [2] Pleomorfik adenomlar benign karakterli, mikst tipte bir tümördür ve etyolojisi tam olarak aydınlatılamamıştır. Yapılan genetik çalışmalarda pleomorfik adenom ve 8q12 ve 12q15'i tutan aberasyonlar ve klonal kromozom anomalileri tanımlanmıştır.…”