Pleomorphic Adenoma of the Posterior Surface of the Soft Palate Causing Sleep Disturbance: A Case Report

Abstract

Patient: Female, 32Final Diagnosis: Pleomorphic adenomaSymptoms: Sleep disturbanceMedication: —Clinical Procedure: Endoscopic assisted surgerySpecialty: OtolaryngologyObjective:Rare diseaseBackground:Pleomorphic adenoma is the most common benign tumor arising in the salivary gland. The signs and symptoms of pleomorphic adenoma of the minor salivary glands vary, depending on the anatomical site involved. A rare case of pleomorphic adenoma of the posterior surface of the soft palate is reported that caused sleep disturbance, which was resolved with endoscopic surgical treatment.Case Report:A 32-year-old woman experienced snoring and mouth-breathing during sleep. Flexible fiberoptic nasopharyngoscopy imaging of the oropharyngeal passage showed obstruction by a tumor the soft palate, which obstructed the oropharyngeal passage. The tumor was excised using endoscopic-assisted transoral surgery and measure 3×2 cm in diameter. Histopathology showed a benign pleomorphic adenoma of the minor salivary gland. Following surgical excision of the tumor, the patient’s sleep improved.Conclusions:To our knowledge, this is the first case of a pleomorphic adenoma of the posterior surface of the soft palate, causing sleep disturbance, removed by endoscopic-assisted transoral surgery following pre-operative flexible fiberoptic nasopharyngoscopy imaging of the oropharyngeal passage.

Management of a giant pleomorphic adenoma of the soft palate: A case report

“…4 Palatal tumors mainly occurs on the hard palate because majority of minor salivary glands are located in this area. 4 Case studies of PA of soft palate are extremely rare. Only few cases have been reported in the English literature (Table 1).…”

“…4,5 Other sites in the oral cavity include the floor of the mouth, lip, buccal mucosa, tongue, pharynx, and retromolar area. 4 PA may occur at any age, but mainly affect patients from 40 to 60 years of age and has a predilection for women. 6,7 Case studies describing huge PA occurring on soft palate are relatively rare.…”

“…It is also known as “mixed tumor, salivary gland type”, which describes its pleomorphic appearance as opposed to its dual origin from epithelial and myoepithelial elements 3 . PA tumors mostly involve the parotid gland; however, if it occurs in the minor salivary glands, the palate would be the most common site 4,5 . Other sites in the oral cavity include the floor of the mouth, lip, buccal mucosa, tongue, pharynx, and retromolar area 4 .…”

Pleomorphic Adenoma of the Palate with Specific Management: A Case Presentation

“…Surgical excision is the treatment of choice for pleomorphic adenoma [11]. The excision must be complete in order to avoid recurrence.…”

Adenoma pleomorfo vs lesión linfoepitelial benigna. Diagnóstico clínico e histopatológico

“…El adenoma pleomorfo es una neoplasia de gran incidencia en cabeza y cuello, en comparación a la lesión linfoepitelial benigna, con una menor incidencia. Suelen aparecer entre la tercera y quinta década de la vida, teniendo predilección por el sexo femenino, en el caso del adenoma pleomorfo, al igual que la lesión linfoepitelial be- (15). Representan alrededor del 3-10 % de los tumores de la región de cabeza y cuello, además el 50 % de las neoplasias de glándulas salivales se caracterizan por ser tumores de crecimiento lento, asintomático, de consistencia firme y cubierta por piel o mucosa sana (16).…”