Pleomorphic adenoma of the trachea: A case report and review of the literature

Liao, Qian-Nuan; Fang, Ze-Kui; Chen, Shu-Bing; Fan, Huizhen; Chen, Lichang; Wu, Xiping; He, Xin; Yu, Huapeng

doi:10.12998/wjcc.v8.i23.6021

Cited by 1 publication

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“…In general, tracheal PA show no difference in gender distribution, but there are differences in age distribution. In the study of Qian-Nuan et al, [9] it was pointed out that tracheal PA tend to occur in middle age, with an average age of 48 years old, which is consistent with the age at which tracheal PA occur in this study. However, there are also reports of special cases.…”

Section: Clinical Features Of Pasupporting

confidence: 91%

Analysis of clinical features of 7 cases of primary pleomorphic adenoma of lower respiratory tract and review of literature

Chen,

Zhang,

2023

Medicine

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To investigate the clinical characteristics of patients with primary pleomorphic adenoma of the lower respiratory tract. The clinical manifestations, laboratory results, pathological and imaging, treatment and prognosis of 7 patients with primary pleomorphic adenoma of the lower respiratory tract who were treated in Hunan Provincial People’s Hospital from December 2015 to May 2020 were analyzed. Among the 7 patients, 5 patients had cough and expectoration as the main clinical manifestations, and the other 2 patients had no symptoms. Pleomorphic adenomas of the lower respiratory tract are mostly located in the trachea or bronchus, and the chest computed tomography findings are circular or ellipsoid masses, or flake high-density shadows and local thickening of the tracheobronchial wall. Tumor histological features and immunohistochemistry can diagnose pleomorphic adenoma and its origin. In this study, 2 asymptomatic patients refused further treatment, 1 survived for more than 3 years, and the other was lost to follow-up during follow-up. One patient with surgical resection was followed up for 5 years after surgery and had a good survival status. The other 4 patients with respiratory symptoms who could not undergo surgery were mainly treated with bronchoscopic interventional therapy on demand, and the survival time up to now was 2 to 5 years. Primary pleomorphic adenoma of the lower respiratory tract is rare in clinic. Its clinical symptoms are related to the location and size of the tumor. Both surgical resection and bronchoscopic intervention have a good clinical prognosis. The cause of death of patients with such diseases is mostly dyspnea caused by tumors in the airway. Early diagnosis, timely intervention and regular follow-up can make patients obtain better curative effect.

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Section: Clinical Features Of Pasupporting

confidence: 91%