Pleomorphic Adenoma with a Novel Gene Rearrangement—LINC01606::PLAG1

Naik, Udit; Amin, Sara E.; Elsayad, Mahmoud; Saluja, Karan

doi:10.1007/s12105-024-01612-x

Head and Neck Pathol

2024

DOI: 10.1007/s12105-024-01612-x

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Pleomorphic Adenoma with a Novel Gene Rearrangement—LINC01606::PLAG1

Udit Naik,

Sara E. Amin,

Mahmoud Elsayad

et al.

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2024

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Cited by 2 publications

References 17 publications

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Insights into the molecular alterations of PLAG1 and HMGA2 associated with malignant phenotype acquisition in pleomorphic adenoma

de Lima-Souza,

Vieira,

Kimura

et al. 2024

Critical Reviews in Oncology/Hematology

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Insights into the molecular alterations of PLAG1 and HMGA2 associated with malignant phenotype acquisition in pleomorphic adenoma

de Lima-Souza,

Vieira,

Kimura

et al. 2024

Critical Reviews in Oncology/Hematology

View full text Add to dashboard Cite

Myoepithelial‐Rich Pleomorphic Adenoma With Novel PLAG1 Inversion on Chromosome 8, and LRP1B, PBRM1 and TCF3 Mutations

Gonzalez,

Pei,

Rong

et al. 2024

Cytopathology

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Pleomorphic adenoma (PA) is the most common salivary gland neoplasm worldwide (50%–70%). Most cases of PA are straightforward diagnoses. However, the diagnosis may be challenging due to the morphological diversity of PAs, which in many cases is caused by the predominance of one of the three components or the presence of metaplastic epithelium. We present the case of a 64‐year‐old male with a history of prostate cancer and right submandibular gland excision 16 years ago with an unknown previous diagnosis and recent regrowth of his mass in the surgical bed. The tumour showed a predominant spindle cell morphology, cytokeratin‐positivity, variable expression of myoepithelial markers in the cytology and surgical pathology specimens, and novel inversion of the chromosome 8, and LRP1B, PBRM1 and TCF3 mutations.

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Pleomorphic Adenoma with a Novel Gene Rearrangement—LINC01606::PLAG1

Cited by 2 publications

References 17 publications

Insights into the molecular alterations of PLAG1 and HMGA2 associated with malignant phenotype acquisition in pleomorphic adenoma

Insights into the molecular alterations of PLAG1 and HMGA2 associated with malignant phenotype acquisition in pleomorphic adenoma

Myoepithelial‐Rich Pleomorphic Adenoma With Novel PLAG1 Inversion on Chromosome 8, and LRP1B, PBRM1 and TCF3 Mutations

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