Pleural Effusion in Pulmonary and Extrapulmonary Blastomycosis

Liang, Yan; Rohra, Prih; Cheng, Lin; Gattuso, Paolo

doi:10.1159/000500973

Cited by 4 publications

(2 citation statements)

References 31 publications

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“…63 In one series, 58.3% of the patients with blastomycosis had unilateral or bilateral effusions. 82 Notably, mediastinal and hilar lymphadenopathy are uncommon in pulmonary blastomycosis (approximately 10%) 63 unlike with other endemic fungi such as acute pulmonary histoplasmosis (>60%) 83 or coccidioidomycosis (40%). 84 A subset of patients with acute pulmonary blastomycosis progresses to ARDS.…”

Section: Clinical Findingsmentioning

confidence: 99%

Endemic Fungi Presenting as Community-Acquired Pneumonia: A Review

Azar

Malo

Hage

2020

Semin Respir Crit Care Med

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AbstractIn endemic areas, dimorphic fungal infections due to Histoplasma capsulatum, Blastomyces dermatitidis, and Coccidioides posadasii/immitis account for up to 30% of cases of community-acquired pneumonia. Because respiratory manifestations are often indistinguishable from common bacterial causes of pneumonia, the diagnosis of pulmonary histoplasmosis, blastomycosis, and coccidioidomycosis is often delayed and associated with antibiotics overuse. In addition to being highly endemic to certain regions of North America, dimorphic fungi have global significance due to established areas of endemicity in all six inhabited continents, an increasingly interconnected world of travelers and transported goods, and a changing epidemiology as a result of global heating and anthropomorphic land utilization. In this review, we discuss the epidemiology, pathogenesis, clinical presentation, diagnostic modalities, and treatment strategies for histoplasmosis, blastomycosis, and coccidioidomycosis.

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Section: Clinical Findingsmentioning

confidence: 99%

Endemic Fungi Presenting as Community-Acquired Pneumonia: A Review

Azar

Malo

Hage

2020

Semin Respir Crit Care Med

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“…North America [7]. The southeastern central states bordering the Mississippi river basins, the Canadian provinces the Great Lakes, the midwestern York and Canada area along the River are all endemic of Blastomycosis also reported sporadically in Nigeria, Zimbabwe, Israel, Lebanon, India, Arabia [1].…”

Section: Many Blastomycosis Cases Have Beenmentioning

confidence: 99%

A Rare Case of Recurrent Blastomycosis in North America

Fatima

2020

IJMPCR

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Blastomycosis is a chronic granulomatous and suppurative mycoses caused by Blastomyces dermatitidis. The majority of cases show a primary pulmonary disease. We report a 65-year-old male patient with two painless, violaceous nodules over the left chest wall and right inner thigh. Initially, differential diagnoses of disseminated Blastomycosis, Pneumonia, and Diffuse large B-cell lymphoma made based on past and present clinical history and presentation. The final diag-nosis of disseminated with secondary cutaneous Blastomycosis in a followup case of Diffuse large B-cell lymphoma made based on skin biopsy, broncho-alveolar lavage, and bronchial brushing showing budding yeasts of Blastomyces. The patient responded well to therapy with Amphotericin B and Itraconazole along with intravenous methylprednisolone.

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Emerging Fungal Infections of the Central Nervous System in the Past Decade: A Literature Review

Lino,

Guimarães,

Sousa

et al. 2024

Infectious Disease Reports

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Introduction: Invasive fungal infections affecting the central nervous system (CNS) are a major health concern worldwide associated with high mortality rates. Their increased incidence is largely due to an increase in the vulnerable immunocompromised population, changing environmental factors, and development of more accurate diagnostic methods. The aim of this article is to identify fungal causes of CNS infections that are recently emerging or have the potential to become emerging pathogens in the near future, as well as their clinical characteristics, including: Candida auris, Trichosporon spp., Blastomyces spp., Sporothrix spp., Talaromyces marneffei, Lomentospora prolificans, and Scedosporium spp. Methods: A review of the literature in PubMed in the last ten years was conducted to identify central nervous system infections caused by each of these fungi. Results: The review identified 10 cases caused by C. auris, 5 cases by Trichosporon spp., 82 cases by Blastomyces spp., 36 cases by Sporothrix spp., 21 cases by T. marneffei, 22 cases by Lomentospora prolificans, and 42 cases by Scedosporium spp. Discussion: The exact burden of these diseases remains difficult to ascertain, but their apparent rise underscores the urgent need for improved diagnostic, treatment, and management strategies against CNS fungal pathogens to improve outcomes against these life-threatening infections.

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Pleural Effusion in Pulmonary and Extrapulmonary Blastomycosis

Cited by 4 publications

References 31 publications

Endemic Fungi Presenting as Community-Acquired Pneumonia: A Review

Endemic Fungi Presenting as Community-Acquired Pneumonia: A Review

A Rare Case of Recurrent Blastomycosis in North America

Emerging Fungal Infections of the Central Nervous System in the Past Decade: A Literature Review

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