Plexiform schwannoma in the maxillary alveolar ridge

Abstract

Schwannomas are benign tumors of the peripheral nerve sheath originating from Schwann cells, which can manifest in head and neck regions and are rare in the oral cavity, especially their involvement in the maxillary alveolar ridge, which is even more atypical. Among all its variants, plexiform schwannoma is characterized by an intraneural multinodular growth.Its differential diagnosis of plexiform neurofibroma is justified by the fact that the latter is pathognomonic for neurofibromatosis and carries great risks of malignancy. In this paper, we present a rare clinical case report of a plexiform schwannoma in a gingival alveolar ridge in a 33-year-old male patient, in which we describe his clinical, histopathological, immunohistochemical aspects and his due approach which, after incisional biopsy diagnosed with plexiform schwannoma, was approached for excision of the lesion by the maxillofacial surgery of Hospital das Cínicas, University of São Paulo Medical School, as well as their respective 7, 14 and 30 day postoperative periods, no signs of recurrence so far. Therefore, in these cases, we emphasize the importance of a thorough clinical examination and the need for additional tests, such as histopathological and immunohistochemical analyzes to determine the correct diagnosis and promote the appropriate treatment.

The Occurrence of a Rare Mandibular Retromolar Triangle Schwannoma and Its Differentiation from Other Rare and Atypical Oral Cavity Tumours

“…This type of SC is rare but is characterised by submucosal swelling with a greater female predilection [34]. On the other hand, a plexiform schwannoma arising from the maxillary alveolar ridge was reported by Bueno et al In this case, the SC was removed and bone curettage was used for surgical radicalisation followed by local osteoplasty [35]. Currently, oral manifestations of SC at every age are rare and are considered difficult diagnostic challenges [36].…”