2012
DOI: 10.1016/j.pestbp.2012.04.007
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Plumbagin as a new natural herbicide candidate for Sicyon angulatus control agent with the target 8-amino-7-oxononanoate synthase

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Cited by 9 publications
(7 citation statements)
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“…Our laboratory has been performing molecular genetics dissection using the antisense approach to identify new target 8-amino-7-oxononanoate synthase (AONS) on the pathway of biotin biosynthesis and to characterize the phenotypic consequences of lossof-function mutations [6,7]. Biotin biosynthesis is understood in detail in Therefore, inhibition of the enzymes involved in the biotin biosynthesis pathway can cause irreparable damage to plants; for this reason, such enzymes can be useful targets for the rational design of inhibitors in the hopes of finding new herbicides [4,5].…”
Section: Discussionmentioning
confidence: 99%
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“…Our laboratory has been performing molecular genetics dissection using the antisense approach to identify new target 8-amino-7-oxononanoate synthase (AONS) on the pathway of biotin biosynthesis and to characterize the phenotypic consequences of lossof-function mutations [6,7]. Biotin biosynthesis is understood in detail in Therefore, inhibition of the enzymes involved in the biotin biosynthesis pathway can cause irreparable damage to plants; for this reason, such enzymes can be useful targets for the rational design of inhibitors in the hopes of finding new herbicides [4,5].…”
Section: Discussionmentioning
confidence: 99%
“…In mutant plants with reduced amounts of glutamine synthetase activity, the target of glufosinate, reduction in glutamine synthetase activity of only 38% was sufficient to cause severe abnormalities Based on knowledge of pathway dynamics, such directed knock-outs can allow the screening of enzymes whose inhibition might be expected to have catastrophic effects in the plant. Hwang et al [6,7] argued that our knowledge of biochemical pathways in plants is incomplete, and the next major herbicide target may lie in an unexpected area of plant metabolism; knowledge in detail of how plants actually die as a result of inhibition of certain known targets is still ambiguous [25]. However, it can be predicted that herbicidal activity is somewhat connected with reducing the level of the target enzyme activity which leads to plant death.…”
Section: Discussionmentioning
confidence: 99%
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“…The specific compounds isolated from plant extracts were identified as described previously [65]. Briefly, each tissue was harvested and prepared following drying at room temperature for five days under shade conditions.…”
Section: Methodsmentioning
confidence: 99%
“…Из листьев Plumbago auriculata (Lam.) Spach выделено природное соединение плюмбагин (5-гидрокси-2-метил-1,4-нафтохинон), которое было эффективно в полевых условиях против ряда однодольных и двудольных сорных растений (31). Аилантон из Ailanthus altissima (Mill.)…”
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