Plumbagin quantification in roots of Plumbago scandens L. obtained by different extraction techniques

Paiva, Selma Ribeiro de; Lima, Lucinlene A; Figueiredo, Maria Raquel; Kaplan, Maria Auxiliadora Coelho

doi:10.1590/s0001-37652004000300004

Cited by 42 publications

(22 citation statements)

References 10 publications

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“…Similarly, degradation and reduced content of plumbagin due to prolonged extraction time was reported in Plumbago scandens. [21] The results obtained from CSE do not show significant variation in amount of mangiferin with the increase of time period. CSE period when increased from 240 to 480 min the content of mangiferin decreased or remained constant (Table 2).…”

Section: Resultsmentioning

confidence: 82%

Optimization of Extraction Techniques and RP-HPLC Analysis of Antidiabetic and Anticancer Drug Mangiferin from Roots of ‘Saptarangi’ (Salacia chinensis L.)

Chavan¹,

Ghadage²,

Kshirsagar

et al. 2015

Journal of Liquid Chromatography & Related Technologies

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Saptarangi (Salacia chinensis L.) is a chief source of mangiferin, which has antidiabetic and anticancer properties. Extraction using continuous shaking extraction (CSE), ultrasonic extraction (UE), microwave assisted extraction (MAE), and steam bath assisted extraction (SBAE) were evaluated for extraction of mangiferin (MF) from roots of S. chinensis. The extracts were analyzed by reverse phase-high performance liquid chromatography (RP-HPLC) and Fourier transform-infra red spectroscopy (FT-IR) analysis. Operational parameters such as different solvents and exposure period were also evaluated. N,N-Dimethyl formamide (DMF 30%, v/v) extracted higher quantity of MF compared to other solvents. The results shows that the extraction of MF by SBAE was more efficient followed by MAE, CSE, and UE methods. Maximum quantity of MF (391.80 ppm) was obtained by SBAE technique and DMF (30%) as a solvent system. SBAE is the easiest and best method for screening of MF from S. chinensis. Furthermore, use of FT-IR validates the RP-HPLC technique for identification and quantification.

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Section: Resultsmentioning

confidence: 82%

Optimization of Extraction Techniques and RP-HPLC Analysis of Antidiabetic and Anticancer Drug Mangiferin from Roots of ‘Saptarangi’ (Salacia chinensis L.)

Chavan¹,

Ghadage²,

Kshirsagar

et al. 2015

Journal of Liquid Chromatography & Related Technologies

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“…Um estudo fi toquímico das folhas mostrou, além da presença de cumarinas, fl avonóides, saponinas e taninos, sendo sua atividade antiinfl amatória e broncodilatadora demonstrada experimentalmente (Leal et al, 2000). Plumbago scandens L. (Louco) -A planta apresenta a naftoquinona plumbagina que demonstrou atividade anticâncer, leishmanicida e bactericida, sendo esta substância também efetiva contra insetos (Paiva et al, 2004) Sansevieria cylindrica Bojer (Rabo-de-tatu) -É relatada a presença de uma saponina esteroidal sem efeitos hemolíticos in vitro que demonstrou inibição na permeabilidade capilar (Antunes et al, 2003). Ximenia americana L. (Ameixa) -Tanto o extrato da casca, bem como das folhas e dos talos tiveram sua atividade fungicida comprovada experimentalmente (Omer;Elnima, 2003), porém pouco se sabe sobre sua composição química.…”

Section: Categoria 3 Plantas Pouco Conhecidas Quimicamente E Com Algunclassified

Plantas medicinais usadas pelos índios Tapebas do Ceará

Morais¹,

Dantas²,

Silva³

et al. 2005

Rev. bras. farmacogn.

122

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RESUMO:Este trabalho apresenta um levantamento das plantas medicinais utilizadas pelos índios Tapebas do Ceará, na tentativa de resgatar a cultura descaracterizada ao longo dos anos. Os parâmetros considerados foram a freqüência de uso das plantas e suas indicações populares para determinadas doenças, baseando-se em entrevistas realizadas nas comunidades localizadas no município de Caucaia, situado a 16 Km de Fortaleza, capital do Ceará, em que foram mencionadas 63 plantas. Amostras das plantas foram coletadas e depositadas no Herbário Prisco Bezerra da Universidade Estadual do Ceará, onde foram identifi cadas. As plantas mais citadas foram agrupadas de acordo com seus dados químico, farmacológico e/ou toxicológico encontrados na literatura científi ca. A pesquisa mostra que a comunidade indígena dos Tapebas faz uso de muitas espécies vegetais sem dados químico e farmacológico registrados, bem como de outras que já foram alvo de pesquisa científi ca, mas que necessitam ainda de estudos complementares para garantir segurança para um uso geral e preparação de fi toterápicos.Unitermos: Plantas medicinais, índios, Tapebas, Ceará. ABSTRACT: "Ethno-medicinal plants of Tapeba Indians from the State of Ceará -Brazil".This work presents a survey of the medicinal plants used by Tapebas Indians from the state of Ceará -Brazil, trying to rescue their culture which is vanishing through the years. Several interviews were performed at the indian's community located at municipality of Caucaia, 16 Km away from Fortaleza, Capital city of the state of Ceará. A total of 63 plants were cited. The interviews were based on the frequency that the plants are used and their respective uses. Samples of the plants were collected and classifi ed by botanists of the Prisco Bezerra Herbarium of the Universidade Federal do Ceará. A literature survey was carried out with all known plants to obtain chemical, pharmacological and toxicological informations. The results show that the Tapebas use plants with no reported chemical and pharmacological informations and other plants which were already studied but need yet more studies to assure complete safety for a general use and production of phytoterapics.

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“…is known to have a regulatory property for blood circulation and inflammatory disease [1,2]. This natural product is one of the major drugs used in the Chinese traditional medicine Da Huang Zhe Chong pill to treat hepatic cirrhosis [3], atherosclerosis, and menstrual disturbance [4]; these actions are probably produced by pharmacodynamic activity on vascular system. Up to now, there have been only a few researches on the chemical componets of Tabanus bivittatus Mat.…”

Section: As a Traditional Chinese Medicine Tabanus Bivittatusmentioning

confidence: 99%

Analysis Fatty Acids Profile in Tabanus bivittatus Mats with Gas Chromatography-Mass Spectrometry

Wang¹,

Fuhua²,

Zhaohan³

et al. 2015

TOBIOTJ

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Tabanus bivittatus Mats., a traditional Chinese medicine, is commonly used for cardiovascular disorders treatment including atherosclerosis. There have been only a few researches on its chemical components, and no detailed report has appeared on its fatty acids. To develop a simple and effective method for the extraction of total fatty acids from Tabanus bivittatus Mats., the Soxhlet extraction (SE) condition was optimized with response surface methodology. The fatty acid composition of the extract were determined by GC-MS with previous derivatization to fatty acid methyl esters (FAMEs). The major fatty acids in Tabanus bivittatus Mats. were oleic acid, palmitic acid, linoleic acid, palmitoleic acid, and stearic acid, and the unsaturated fatty acids occupy 63.9% of the total fatty acids.

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Plumbagin quantification in roots of Plumbago scandens L. obtained by different extraction techniques

Cited by 42 publications

References 10 publications

Optimization of Extraction Techniques and RP-HPLC Analysis of Antidiabetic and Anticancer Drug Mangiferin from Roots of ‘Saptarangi’ (Salacia chinensis L.)

Optimization of Extraction Techniques and RP-HPLC Analysis of Antidiabetic and Anticancer Drug Mangiferin from Roots of ‘Saptarangi’ (Salacia chinensis L.)

Plantas medicinais usadas pelos índios Tapebas do Ceará

Analysis Fatty Acids Profile in Tabanus bivittatus Mats with Gas Chromatography-Mass Spectrometry

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