PM417 Assessing endothelial function in type-2-diabetes mellitus using ECG-gated retinal artery flicker provocation and digital reactive hyperaemia (Endopat®)

Lal, Anchal; Thiagalingam, Aravinda; Mitchell, Paul; Gibbs, O.; Barry, Tony; Kovoor, Pramesh

doi:10.1016/j.gheart.2014.03.1748

Cited by 1 publication

(1 citation statement)

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“…By employing short light pulses as a trigger (flickering), DVA can provide precise readouts of the light-induced arterial vasodilation to provide insights into the endothelium of the retinal arteries. More specifically, the vasodilatory mechanism induced refers to the activation of the rods and cones, leading to increased metabolism and oxygen demand, which, in turn, is met by the release of vasodilatory nitric oxide (NO) and an increase in local blood flow [ 47 ].…”

Section: Diabetic Retinopathymentioning

confidence: 99%

Clinical and Translational Imaging and Sensing of Diabetic Microangiopathy: A Narrative Review

Fasoula,

Xie,

Katsouli

et al. 2023

JCDD

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Microvascular changes in diabetes affect the function of several critical organs, such as the kidneys, heart, brain, eye, and skin, among others. The possibility of detecting such changes early enough in order to take appropriate actions renders the development of appropriate tools and techniques an imperative need. To this end, several sensing and imaging techniques have been developed or employed in the assessment of microangiopathy in patients with diabetes. Herein, we present such techniques; we provide insights into their principles of operation while discussing the characteristics that make them appropriate for such use. Finally, apart from already established techniques, we present novel ones with great translational potential, such as optoacoustic technologies, which are expected to enter clinical practice in the foreseeable future.

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Section: Diabetic Retinopathymentioning

confidence: 99%