PMH63 Stay Healthy Through Game-Care Therapeutics: It's Time to Play the Game!

Abstract

OBJECTIVES:To understand the association of antidepressant-related weight gain with various aspects of worker productivity. METHODS: Employed individuals (Ն18 years of age) with diagnosed depression (excluding bipolar disorder) completed a web-based computer-generated 25-minute survey (study population identified by Harris Interactive). Weight gain was measured using the Toronto Side Effects Scale which measures medication-related side effects in the 2-weeks preceding the survey, and was analyzed as a 4-level ordinal variable (none, Ͻϭ2lbs, Ͻϭ4lbs, and Ͻϭ7lbs), where "none" was the referent category. The Work Productivity and Activity Impairment (WPAI) questionnaire was used to assess percent of impaired productivity (overall, absenteeism, presenteeism, activity impairment) during the 2-weeks preceding the survey, with higher numbers indicating greater impairment and less productivity (i.e., worse outcomes). Using distribution among current antidepressant users, each WPAI measure was categorized into quintiles, with the lowest and highest representing least and greatest impairment, respectively. Cumulative logit models were used to estimate the overall effect of weight gain on WPAI measures as well as across gender. RESULTS: Of the 1521 survey respondents, 872 (57%) reported current antidepressant use (60.6% female, mean age 49.9 Ϯ 13.5 years). Weight gain was associated with loss of productivity: Ͻϭ2lbs (odds ratio [OR]ϭ 1.54; pϭ0.005), Ͻϭ4lbs (ORϭ 2.14 ; pϭ0.0007 ) and Ͻϭ7lbs (ORϭ 2.96; pϭ 0.0009). In females, using "no weight gain" as a reference group, the odds of being in a worse overall productivity category increased with the increase of weight gain: Ͻϭ2lbs (odds ratio [OR]ϭ1.59; pϭ0.02), Ͻϭ4lbs (ORϭ2.17; pϭ0.005) and Ͻϭ7lbs (ORϭ3.13; pϭ0.01). Similar trends were observed in males: Ͻϭ2lbs (ORϭ1.43; pϭ0.15), Ͻϭ4lbs (ORϭ2.00; pϭ0.06) and Ͻϭ7lbs (ORϭ2.86; pϭ0.02). CONCLUSIONS: In employees with depression, antidepressant-related weight gain was associated with loss in overall productivity. Additional research to quantify the indirect costs of antidepressant-related weight gain in terms of productivity losses may be useful. OBJECTIVES:Health care research in present scenario is a platform wherein a range of interventions play their role to alleviate suffering and mitigate the course of diseases. Gaming console have so far demonstrated promising and considerable potential as rehabilitation and lifestyle treatments. The objective of this review was to study the advent and role of new generation gaming consoles (e.g. Nintendo Wii, Xbox, and PS3) in healthcare research in a systematic manner. METHODS: A consolidated search strategy was developed and run in EMBASE, MEDLINE, Cochrane, POPLINE, SCOPUS, and Clinicaltrials.gov databases to identify the trials utilising gaming consoles as principal intervention or supportive treatment in various disease areas. Grey literature was also identified though Google Scholar. Data extraction was performed and results were summarized. RESULTS: The data revealed that motion senso...