1974
DOI: 10.1016/s0140-6736(74)91344-0
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Pneumatic Compression of the Calf and Postoperative Deep-Vein Thrombosis

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Cited by 40 publications
(12 citation statements)
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“…The majority of trials assessing compression methods were conducted in a surgical setting: 14 were orthopaedic, 24,33,34,36,40,48,49,[51][52][53]59,60,63,64 16 general, 23,25,26,28,29,32,[37][38][39]41,42,44,50,54,61,62 six neurosurgical or after spinal surgery, 31,43,[55][56][57][58] three gynaecological 30,45,46 and one mixed surgical, 47 with only two trials 27,35 conducted among 257 medical patients at high risk of venous thromboembolism. After subdividing these trials into those assessing monotherapy and those assessing adjunctive therapy, the specific type of surgical or medical setting did not appear to influence the effectiveness of mechanical compression [heterogeneity 2 for monotherapy (on 5 df) = 4.6; p > 0.1, and heterogeneity 2 for adjunctive therapy (on 2 df) = 3.7; p > 0.1, not significant (NS); Figure 2].…”
Section: Description Of Trialsmentioning
confidence: 99%
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“…The majority of trials assessing compression methods were conducted in a surgical setting: 14 were orthopaedic, 24,33,34,36,40,48,49,[51][52][53]59,60,63,64 16 general, 23,25,26,28,29,32,[37][38][39]41,42,44,50,54,61,62 six neurosurgical or after spinal surgery, 31,43,[55][56][57][58] three gynaecological 30,45,46 and one mixed surgical, 47 with only two trials 27,35 conducted among 257 medical patients at high risk of venous thromboembolism. After subdividing these trials into those assessing monotherapy and those assessing adjunctive therapy, the specific type of surgical or medical setting did not appear to influence the effectiveness of mechanical compression [heterogeneity 2 for monotherapy (on 5 df) = 4.6; p > 0.1, and heterogeneity 2 for adjunctive therapy (on 2 df) = 3.7; p > 0.1, not significant (NS); Figure 2].…”
Section: Description Of Trialsmentioning
confidence: 99%
“…In 19 trials [40][41][42][43][44][45][46][47][48][49][50][51][52][53][54][55][56][57][58] among 2255 patients assessing IPC as monotherapy, IPC produced a highly significant 66% (7) reduction in DVT [112/1108 (10.1%) IPC vs 268/1147 (23.4%) control, 2p < 0.00001; Figure 5a]. There was marginal evidence of heterogeneity of effect among these trials ( 2 on 16 df = 28.4; p = 0.03), but this was generated chiefly by one trial.…”
Section: Intermittent Pneumatic Compressionmentioning
confidence: 99%
“…The incidence of asymptomatic DVT was 30% in the unstimulated group and Effect of intermittent pneumatic compression (IPC) in the prevention of deep vein thrombosis (DVT) diagnosed by surveillance with objective methods (fibrinogen uptake test or phlebography) in nonorthopaedic surgical randomized controlled studies (*contralateral leg was used as the control). [113][114][115][116][117][118][119][120][121][122] 14% in the stimulated group (OR 0.35; 95% CI 0.90-1.16). In this RCT, perfusion lung scanning and chest x-rays were performed on the day before operation and 4 to 6 days after operation.…”
Section: Prophylactic Methods and Recommendationsmentioning
confidence: 99%
“…However, both electrical stimulation of the calf muscles and intermittent compression of the leg are effective in reducing thrombosis, probably by emptying areas of extreme venous stasis at the valve cusps within the calf muscles (Browse et al, 1974). Several studies have now shown that a simple intermittent compression machine which squeezes the calf muscles during, and for 24 hr after operation greatly reduces the incidence of thrombosis (Clark et al, 1974;Roberts and Cotton, 1974).…”
Section: Prophylaxismentioning
confidence: 99%