2018
DOI: 10.1155/2018/6931747
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Pneumatosis Coli Formation via Counterperfusion Supersaturation in a Patient with Severe Diarrhea

Abstract: We present the case of an elderly male patient with known multiple myeloma who was hospitalized with profuse watery diarrhea and abdominal pain after a course of induction chemotherapy. Intestinal intramural gas was found on imaging and the diagnosis of pneumatosis intestinalis was confirmed by colonoscopy. We propose counterperfusion supersaturation as the etiology for this patient's pneumatosis coli via disruption of homeostasis between nitrogen and hydrogen normally present in the bowel. His condition was s… Show more

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“…The etiology, both for primary and secondary PI, remains unclear. More than 60 causative diseases and conditions have been identified, but the specific pathophysiology remains unknown [11,16,20,26,127,138,173].…”
Section: Discussionmentioning
confidence: 99%
“…The etiology, both for primary and secondary PI, remains unclear. More than 60 causative diseases and conditions have been identified, but the specific pathophysiology remains unknown [11,16,20,26,127,138,173].…”
Section: Discussionmentioning
confidence: 99%