Pneumatosis intestinalis in Crohn's disease

González-Olivares, C.; Palomera-Rico, Ana; Blanca, Nieves Romera-Pintor; Sánchez-Aldehuelo, Rubén; Figueroa-Tubío, Alexandre; Filia, Irene García de la; López-Sanromán, Antonio

doi:10.1016/j.gastre.2019.02.017

Cited by 2 publications

(3 citation statements)

References 5 publications

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“…During the course of her disease, she required 2 ileocolic resections, of which, one of them was complicated by anastomotic dehiscence. Later, when she presented with her usual mild abdominal discomfort, a follow-up CT scan included cystic pneumatosis intestinalis in the ascending and transverse colon [ 4 ]. Another case reported a 58-year-old female patient with long-standing Crohn’s disease complicated by strictures requiring two ileal resection and treatment with sulfasalazine and azathioprine.…”

Section: Discussionmentioning

confidence: 99%

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Pneumatosis Intestinalis Manifesting as an Atypical Presentation of Crohn’s Disease

Vallejo,

Gheit,

Nagi

et al. 2024

Cureus

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Crohn’s disease is an inflammatory bowel disease that has a bimodal distribution, occurring most frequently between ages 15 to 30 years and 40 to 60 years. It presents with a relapsing and remitting course. The most common area involved is the terminal ileum and right colon and the inflammation oftentimes leads to non-caseating granulomas and ulcerations in both the superficial mucosa and deeper layers. Additionally, pneumatosis intestinalis is defined as the presence of gas and free air in the extraluminal space of the intestines which is an abnormal occurrence and correlates with underlying pathology. There are only a few cases reported in the literature that present pneumatosis intestinalis in the setting of, and possibly linked to, Crohn’s disease. Our case presents an elderly male patient with jejunal ulcerations and strictures suggesting Crohn’s disease and associated pneumatosis intestinalis as evidenced on outpatient computed tomography (CT) enterography. Upon presentation to the hospital, the patient was non-toxic and was not complaining of any pain. During his inpatient stay, there was a suspicion of Crohn’s disease and therefore he was started on Infliximab therapy. We will review the possible pathogenesis of Crohn’s disease and other cases presenting pneumatosis intestinalis in the setting of Crohn’s disease.

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Section: Discussionmentioning

confidence: 99%

“…However, it is important to consider it can be secondary to highly diverse causes, including infection, inflammation, and iatrogenic reasons. The onset of it can occur in patients with inflammatory bowel disease, and when a clinically benign finding, conservative management may be employed [ 4 ].…”

Section: Discussionmentioning

confidence: 99%

Pneumatosis Intestinalis Manifesting as an Atypical Presentation of Crohn’s Disease

Vallejo,

Gheit,

Nagi

et al. 2024

Cureus

View full text Add to dashboard Cite

show abstract

“…2 It usually related to respiratory infections, tumor or collagen disease, traumas, immunosuppression. [3][4][5] Treatment plan to PCI patients depend on underlying cause, and clinical condition severity.…”

Section: Introductionmentioning

confidence: 99%

Pneumatosis cystoides intestinalis – an incidental finding with unpredictable evolution

Santos

Silva

et al. 2020

Journal of Coloproctology

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Pneumatosis cystoides intestinalis is an uncommon disease with unknown etiology characterized by the presence of multiple gas-filled cysts within the submucosa or subserosa of the intestinal wall. Pneumoperitoneum and/or intestinal perforation are complications that may be associated with pneumatosis cystoides intestinalis. The patients are often prone to misdiagnosis or mistreatment. We are presenting a case of pneumatosis cystoides intestinalis in a 42 year-old woman affected by peritoneal free air and numerous, diffuse, bubble-like intramural gas collections into the jejunum and ileum, showed in CT-enterography images. The woman had a carcinoid tumor located in jejunum two years ago, treated with enterectomy. Recent complaints of nonspecific symptoms of abdominal discomfort and diarrhea motivated the realization of CT scan, serum chromogranin and urine 5-hidroxindolacetic acid for hypothesis of tumor carcinoid recurrence withdraw. The only change found was the presence of pneumatosis cystoides intestinalis in CT-enterography images without intestinal necrosis, bleeding or evident obstruction. For that reason no surgical procedure was realized and the patient stayed on surveillance. Actually, the patient complaints are sporadic abdominal discomfort, without pneumatosis cystoides intestinalis clinical evidence. Conclusion The treatment plan of patient with PCI depends on underlying cause and clinical condition severity. When conservative treatment is adopted the clinical evolution of pneumatosis cystoides intestinalis is unpredictable and can even disappear in an indeterminate number of patients.

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Pneumatosis intestinalis in Crohn's disease

Cited by 2 publications

References 5 publications

Pneumatosis Intestinalis Manifesting as an Atypical Presentation of Crohn’s Disease

Pneumatosis Intestinalis Manifesting as an Atypical Presentation of Crohn’s Disease

Pneumatosis cystoides intestinalis – an incidental finding with unpredictable evolution

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