Pneumococcal purpura fulminans in a 25-year-old patient with liver cirrhosis due to autoimmune hepatitis

We report a previously healthy woman in her 50s who presented with sepsis, rapidly progressive purpuric rash and disseminated intravascular coagulation. She was diagnosed with acute infective purpura fulminans due to invasive pneumococcal infection likely secondary to sinusitis. Our case report discusses our initial diagnostic uncertainty and approach in investigating and treating such a critically unwell patient.

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Purpura fulminans in a hyposplenic patient arising from pneumococcal sinusitis

Tew

Johnson

Louis

et al. 2023

BMJ Case Rep

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Púrpura fulminans secundaria a meningococcemia con desenlace fatal: Reporte de caso y revisión de la literatura

Orozco Jiménez,

Agudelo-Rojas,

Mejía-Giraldo

et al. 2024

rev. asoc. colomb. dermatol. cir. dematol.

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La púrpura fulminante (PF) es una presentación infrecuente de la meningococcemia secundaria a trombosis intravascular e infarto hemorrágico cutáneo. Su curso es potencialmente letal, con tasas de mortalidad en la fase aguda entre 18-40%. Afecta con mayor frecuencia a lactantes, donde los casos en adultos se limitan a reportes de la literatura. Presentamos el caso de un paciente con meningococcemia asociado a púrpura fulminante que requirió de amputación transtibial bilateral más amputación de las falanges distales de ambas manos. La púrpura fulminante (PF) es una presentación infrecuente de la meningococcemia secundaria a trombosis intravascular e infarto hemorrágico cutáneo. Su curso es potencialmente letal, con tasas de mortalidad en la fase aguda entre 18-40%. Afecta con mayor frecuencia a lactantes, donde los casos en adultos se limitan a reportes de la literatura. Presentamos el caso de un paciente con meningococcemia asociado a púrpura fulminante que requirió de amputación transtibial bilateral más amputación de las falanges distales de ambas manos.

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Pneumococcal purpura fulminans in a 25-year-old patient with liver cirrhosis due to autoimmune hepatitis

Cited by 2 publications

References 15 publications

Purpura fulminans in a hyposplenic patient arising from pneumococcal sinusitis

Purpura fulminans in a hyposplenic patient arising from pneumococcal sinusitis

Púrpura fulminans secundaria a meningococcemia con desenlace fatal: Reporte de caso y revisión de la literatura

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