Pneumococcal Vaccination Rates in Children With Sickle Cell Disease

Abstract

Barriers to completing age-appropriate recommended pneumococcal immunizations should be identified and addressed to further reduce invasive pneumococcal disease in this high-risk patient population.

Determining Adherence to Quality Indicators in Sickle Cell Anemia Using Multiple Data Sources

“…A case-control study of pneumococcal vaccine adherence (PCV7 and PPV) in Michigan using Medicaid claims data between 2001 and 2008 revealed 72% of children with SCD received at least one pneumococcal vaccine by age 3 months and 73% had three documented by age 24 months. 21 These rates are similar to the 73.6% observed in this study. Lower rates of PPV adherence were seen in a retrospective cohort of Wisconsin Medicaid claims conducted between 2003 and 2007, with only 49.8% of children aged 2–18 years adherent with PPV vaccination.…”

“…11–13 Despite this decline, few studies have monitored adherence to vaccination rates. 5,21,22 This study found 73.6% of children received their first PPV at age 2 years. A case-control study of pneumococcal vaccine adherence (PCV7 and PPV) in Michigan using Medicaid claims data between 2001 and 2008 revealed 72% of children with SCD received at least one pneumococcal vaccine by age 3 months and 73% had three documented by age 24 months.…”

Pneumococcal vaccination coverage among children with sickle cell anemia, sickle cell trait, and normal hemoglobin

“…Although children with sickle cell anemia had higher vaccination coverage, up to 45% were still not adequately vaccinated against IPD by 16 months of age. This is slightly lower than previously reported; however, our assessment of PPSV coverage, as well as the indication that children with sickle cell anemia were covered at a higher rate than children without sickle cell disease, are reflective of other findings . Given the significant room for improvement among this particularly vulnerable population, strategies that specifically target this subgroup of the population to increase vaccination coverage are necessary.…”

Implementation of transcranial Doppler ultrasonography screening and primary stroke prevention in urban and rural sickle cell disease populations

“…Rural counties were based on county of residence and HRSA standards for rural health grants [16], which provides identification of rural tracts within metropolitan counties. For this study, outreach clinics were considered as rural since !75% of patients followed in these clinics reside in a county classified as rural and the local GRU clinic was considered as urban since !75% of patients followed in this clinic reside in a county not classified as rural.…”