Pneumococcal vaccination status among cirrhotic patients in Italy: a neglected topic

Stroffolini, Tommaso; Ciancio, Alessia; Federico, Alessandro Di; Benigno, R.; Colloredo, Guido; Lombardi, Anna; Cotugno, Rosa; Verucchi, Gabriella; Ferrigno, Luigina; Gioli, Federico; Marignani, Massimo; Troshina, Yulia; Romeo, Mario; Costanzo, Francesco Di; Niro, G.A.; Badia, Lorenzo

doi:10.1007/s10096-023-04614-9

Eur J Clin Microbiol Infect Dis

2023

DOI: 10.1007/s10096-023-04614-9

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Pneumococcal vaccination status among cirrhotic patients in Italy: a neglected topic

Tommaso Stroffolini

Alessia Ciancio

Alessandro Di Federico

et al.

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2024

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Vaccination in Patients with Liver Cirrhosis: A Neglected Topic

Stroffolini,

Stroffolini

2024

Vaccines

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Patients with liver cirrhosis, due to their weakened innate and adaptive immunity, are more prone to frequent and severe vaccine-preventable infections. Moreover, impaired adaptive immunity results in a limited antibody response to vaccines. Despite this suboptimal antibody response, vaccines have proven to be very effective in reducing severe outcomes and deaths in these patients. In the Western world, regulatory authorities and scientific liver societies (e.g., AASLD and EASL) have recommended vaccinations for cirrhotic patients. However, despite these strong recommendations, vaccine coverage remains suboptimal. Improving vaccine effectiveness and safety information, providing comprehensive counseling to patients, fact-checking to combat fake news and disinformation and removing barriers to vaccination for disadvantaged individuals may help overcome the low coverage rate. In view of this, vaccines should be administered early in the course of chronic liver diseases, as their efficacy declines with the increasing severity of the disease.

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Vaccination in Patients with Liver Cirrhosis: A Neglected Topic

Stroffolini,

Stroffolini

2024

Vaccines

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Pneumococcal vaccination status among cirrhotic patients in Italy: a neglected topic

Cited by 1 publication

References 18 publications

Vaccination in Patients with Liver Cirrhosis: A Neglected Topic

Vaccination in Patients with Liver Cirrhosis: A Neglected Topic

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