Pneumonia and Inflammatory Arthritis Caused by Unusual Occupational Exposure or a Life-Threatening Infection Resulting From a More Commonly Encountered Mechanism?

Vry, Derek J. De; Barker, Paul H.; Vardanyan, Marina; Milosavljevic, Staci L.; Dygert, Timo N.; Jurva, Jason W.; Ballmoos, Moritz C. Wyler Van; Gandhi, Sweeta D.; Almassi, G. Hossein; Pagel, Paul S.

doi:10.1053/j.jvca.2015.01.020

Cited by 2 publications

(2 citation statements)

References 22 publications

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“…In this test, an increasing level of electric current will be applied on the animal’s tail, typically mice or rats [ 110 , 111 ]. The animals will respond via flinching and jumping, followed by a vocalization of pain which will be detected by an ultrasonography detector [ 112 ].…”

Section: Non-inflammatory Behavioral Pain Study In Animal Modelsmentioning

confidence: 99%

Overview of Neurological Mechanism of Pain Profile Used for Animal “Pain-Like” Behavioral Study with Proposed Analgesic Pathways

Yam

Loh

et al. 2020

IJMS

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Pain is the most common sensation installed in us naturally which plays a vital role in defending us against severe harm. This neurological mechanism pathway has been one of the most complex and comprehensive topics but there has never been an elaborate justification of the types of analgesics that used to reduce the pain sensation through which specific pathways. Of course, there have been some answers to curbing of pain which is a lifesaver in numerous situations—chronic and acute pain conditions alike. This has been explored by scientists using pain-like behavioral study methodologies in non-anesthetized animals since decades ago to characterize the analgesic profile such as centrally or peripherally acting drugs and allowing for the development of analgesics. However, widely the methodology is being practiced such as the tail flick/Hargreaves test and Von Frey/Randall–Selitto tests which are stimulus-evoked nociception studies, and there has rarely been a complete review of all these methodologies, their benefits and its downside coupled with the mechanism of the action that is involved. Thus, this review solely focused on the complete protocol that is being adapted in each behavioral study methods induced by different phlogogenic agents, the different assessment methods used for phasic, tonic and inflammatory pain studies and the proposed mechanism of action underlying each behavioral study methodology for analgesic drug profiling. It is our belief that this review could significantly provide a concise idea and improve our scientists’ understanding towards pain management in future research.

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Section: Non-inflammatory Behavioral Pain Study In Animal Modelsmentioning

confidence: 99%

Overview of Neurological Mechanism of Pain Profile Used for Animal “Pain-Like” Behavioral Study with Proposed Analgesic Pathways

Yam

Loh

et al. 2020

IJMS

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“…Within adults, S. capitis infection has resulted in a number of different clinical presentations. These include the following: Native valve endocarditis [ 48 , 49 , 50 , 51 , 52 ]; Prosthetic valve endocarditis [ 53 , 54 , 55 , 56 , 57 , 58 ]; Osteomyelitis [ 59 , 60 , 61 , 62 ]; Polymicrobial infections [ 63 , 64 , 65 , 66 ]; Surgical implant infections [ 67 , 68 , 69 , 70 , 71 ]; …”

Section: Clinical Presentations and Managementmentioning

confidence: 99%

Staphylococcus capitis: Review of Its Role in Infections and Outbreaks

et al. 2023

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In June 2021, a national incident team was formed due to an increased detection of Staphylococcus capitis in samples from hospitalised infants. Staphylococcus capitis has been known to cause outbreaks in neonatal units across the globe, but the extent of the UK spread was unclear. A literature review was undertaken to support case identification, clinical management and environmental infection control. A literature search was undertaken on multiple databases from inception to 24 May 2021, using keywords such as “Staphylococcus capitis”, “NRCS-A”, “S. capitis”, “neonate”, “newborn” and “neonatal intensive care unit” (NICU). After screening, 223 articles of relevance were included. Results show incidences of S. capitis outbreaks have frequently been associated with the outbreak clone (NRCS-A) and environmental sources. The NRCS-A harbours a multidrug resistance profile that includes resistance to beta-lactam antibiotics and aminoglycosides, with several papers noting resistance or heteroresistance to vancomycin. The NRCS-A clone also harbours a novel SCCmec-SCCcad/ars/cop composite island and increased vancomycin resistance. The S. capitis NRCS-A clone has been detected for decades, but the reasons for the potentially increased frequency are unclear, as are the most effective interventions to manage outbreaks associated with this clone. This supports the need for improvements in environmental control and decontamination strategies to prevent transmission.

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Pneumonia and Inflammatory Arthritis Caused by Unusual Occupational Exposure or a Life-Threatening Infection Resulting From a More Commonly Encountered Mechanism?

Cited by 2 publications

References 22 publications

Overview of Neurological Mechanism of Pain Profile Used for Animal “Pain-Like” Behavioral Study with Proposed Analgesic Pathways

Overview of Neurological Mechanism of Pain Profile Used for Animal “Pain-Like” Behavioral Study with Proposed Analgesic Pathways

Staphylococcus capitis: Review of Its Role in Infections and Outbreaks

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