PO.7.162 Epidemiology of systemic lupus erythematosus in central Sweden: a population-based cohort study from the östergötland county over 14 years

Abstract

utilization. The registry will enroll patients who are initiating or who have already initiated treatment with commercial voclosporin within 3 months prior to consent. Patients !18 years of age with biopsy-confirmed lupus nephritis are eligible (Table 1). Secondary objectives include describing at baseline and during the study period the clinical characteristics, treatment and response patterns of patients treated with voclosporin.To date, 36 sites in 16 states have been selected to participate in the registry; Enlight-LN is currently enrolling patients.

Declining Incidence of Systemic Lupus Erythematosus in Norway 1999–2017: Data From a Population Cohort Identified by International Classification of Diseases, 10th Revision Code and Verified by Classification

“…Using the 1997 ACR criteria, the estimated incidence rate for adult SLE (1.6 per 100,000 per year) was low compared to previous smaller-scaled studies from Scandinavia. [24][25][26][27][28] Our data also support a decreasing trend in incidence during the study period. Although effects of other factors, including methodologic, cannot be ruled out, this may reflect a de facto decrease in recent years, in line with previous European population-based studies from Sweden , 24 Italy (2012-2020), 29 and Spain (2002-2006), 30 and from South-Korea (2005-2015).…”

“…Although effects of other factors, including methodologic, cannot be ruled out, this may reflect a de facto decrease in recent years, in line with previous European population‐based studies from Sweden (1981–2006), 24 Italy (2012–2020), 29 and Spain (2002–2006), 30 and from South‐Korea (2005–2015) 31 . In a recently published Swedish study (2008–2021) and a Danish study (1995–2011), the incidence rates were more stable 28,32 33 .…”

“…Using this clinical assessment approach, we confirmed SLE diagnosis in 45% (1,558 per 3,488) of the study cohort, underscoring the challenge of diagnosing SLE in clinical practice. Using the 1997 ACR criteria, the estimated incidence rate for adult SLE (1.6 per 100,000 per year) was low compared to previous smaller‐scaled studies from Scandinavia 24–28 …”

“…31 In a recently published Swedish study (2008-2021) and a Danish study (1995-2011), the incidence rates were more stable. 28,32 data from Crete, Greece, showed a stable incidence from 2010 to 2013, after a prior increase from 1999 to 2010. 33 Only one other populationbased study, from Minnesota, has applied the 2019 EULAR/ ACR criteria.…”