“…In this issue of Pediatric Critical Care Medicine, Cashen et al ( 6) performed a secondary subanalysis of the ICU-RESUS dataset, involving a multicenter, prospective cohort study using 1,100 p-IHCA events from 2016 to 2021 and analyzing the association between sodium bicarbonate administration during p-IHCA and patient outcomes (7). Outcomes included survival to hospital discharge, achievement of return of spontaneous circulation, and survival to hospital discharge with favorable neurologic outcomes.…”