Point-of-care testing of butyrylcholinesterase activity through modulating the photothermal effect of cuprous oxide nanoparticles

Label-Free and Ultrasensitive Detection of Butyrylcholinesterase and Organophosphorus Pesticides by Mn(II)-Based Electron Spin Resonance Spectroscopy with a Zero Background Signal

“…It is an essential indicator for the prediction and diagnosis of many diseases, including liver damage, Alzheimer's disease, and organophosphorus pesticide (OP) poisoning. 1 Therefore, accurate determination of BChE's activity has practical significance. So far, colorimetric and fluorescence methods were most commonly used in the evaluation of BChE's activity.…”

“…Butyrylcholinesterase (BChE) is a nonspecific cholinesterase that can hydrolyze a variety of choline esters. It is an essential indicator for the prediction and diagnosis of many diseases, including liver damage, Alzheimer’s disease, and organophosphorus pesticide (OP) poisoning . Therefore, accurate determination of BChE’s activity has practical significance.…”

Construction of a copper nanocluster/MnO2 nanosheet-based fluorescent platform for butyrylcholinesterase activity detection and anti-Alzheimer's drug screening

“…Butyrylcholinesterase (BChE) is an important member of cholinesterases, which is produced by hepatocytes in liver and released into blood plasma for catalyzing the hydrolysis of choline-based esters. [1][2][3] Liver diseases, such as hepatic cirrhosis, hepatocellular carcinoma, and acute hepatitis, can reduce the production of BChE in the liver, thus leading to a low level of BChE activity in the bloodstream. [4][5][6] Accordingly, BChE activity is one of the most vital bioindicators in the clinical diagnosis of liver diseases.…”