Point-of-care testing of cholesterol and triglycerides for epidemiologic studies: evaluation of the multicare-in system

Rapi, Stefano; Bazzini, Cristina; Tozzetti, Camilla; Sbolci, Valentina; Modesti, Pietro Amedeo

doi:10.1016/j.trsl.2008.11.010

Cited by 53 publications

(39 citation statements)

References 20 publications

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“…The mean of the last two measurements was used for the analysis. As recommended for developing countries, fasting blood glucose (FBG, mg/dL) and TC (mg/dL) were measured from early-morning capillary blood samples,12 13 after an overnight fast. The samples were obtained and analysed at home using a calibrated Accutrend Plus GCTL analyser (Roche Diagnostics, Germany).…”

Section: Methodsmentioning

confidence: 99%

Association of socioeconomic status measured by education, and cardiovascular health: a population-based cross-sectional study

et al. 2014

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ObjectiveCardiovascular health (CVH) is a relatively new concept defined by the American Heart Association (AHA). The aim of the present study was to assess whether the indices of CVH were discriminators of socioeconomic status (SES) in the adult population of the Republic of Srpska (RS).DesignPopulation-based cross-sectional study.SettingRS, Bosnia and Herzegovina.ParticipantsThe study involved 4165 adults aged ≥18 years (mean age 50.2; 54% women) who participated in the National Health Survey performed from September to November 2010 in the RS.Study variablesParticipant's education was a proxy for SES. Potential discriminators of SES were indices of CVH presented according to AHA as: ideal health behaviours index (non-smoking, body mass index <25 kg/m2, physical activity at goal level and healthy diet); ideal health factors index (untreated total cholesterol <200 mg/dL, untreated blood pressure <120/<80 mm Hg, untreated fasting glucose <100 mg/dL and non-smoking); and ideal CVH status (defined as all seven ideal health metrics present) versus intermediate and poor CVH status.ResultsParticipants with high educational levels had a significantly greater number of ideal CVH metrics, and ideal health factor metrics compared with those with low or medium educational level (OR 0.88 95% CI 0.77 to 0.99 and OR 0.88 95% CI 0.80 to 0.96; OR 0.81 95% CI 0.69 to 0.96 and OR 0.77 95% CI 0.68 to 0.87; respectively). The number of ideal behaviour metrics was not a discriminator of educational groups. Concerning the categories of CVH status the poor CVH was a discriminator for low and medium education compared with those with high education (OR 1.93 95% CI 1.24 to 3.01 and OR 1.54 95% CI 1.08 to 2.19, respectively).ConclusionsOur findings emphasise the large potential for preventing cardiovascular disease, showing a low proportion with a favourable CVH profile, especially among low-educated people. It is necessary to consider prevention strategies aimed at improving CVH in RS, targeting primarily low educational groups.

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Section: Methodsmentioning

confidence: 99%

Association of socioeconomic status measured by education, and cardiovascular health: a population-based cross-sectional study

et al. 2014

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“…Some of the small POCT cholesterol systems include Accutrend Plus (Roche Diagnostics), CardioChek PA (PTS Diagnostics, Indianapolis, IN), and MultiCare-in (BSI, Arezzo, Italy). 147 MultiCare systems are pocket-sized reflectance photometers in which the color intensity from a chromogen reaction is proportional to the concentration of cholesterol or triglycerides in blood. A drop of capillary blood is applied to the test strip to obtain results for cholesterol and triglyceride assays.…”

Section: Chronic Diseases: Monitoring and Diagnosticsmentioning

confidence: 99%

Development and Applications of Portable Biosensors

2015

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The significance of microfluidics-based and microelectromechanical systems-based biosensors has been widely acknowledged, and many reviews have explored their potential applications in clinical diagnostics, personalized medicine, global health, drug discovery, food safety, and forensics. Because health care costs are increasing, there is an increasing need to remotely monitor the health condition of patients by point-of-care-testing. The demand for biosensors for detection of biological warfare agents has increased, and research is focused on ways of producing small portable devices that would allow fast, accurate, and on-site detection. In the past decade, the demand for rapid and accurate on-site detection of plant disease diagnosis has increased due to emerging pathogens with resistance to pesticides, increased human mobility, and regulations limiting the application of toxic chemicals to prevent spread of diseases. The portability of biosensors for onsite diagnosis is limited due to various issues, including sample preparation techniques, fluid-handling techniques, the limited lifetime of biological reagents, device packaging, integrating electronics for data collection/analysis, and the requirement of external accessories and power. Many microfluidic, electronic, and biological design strategies, such as handling liquids in biosensors without pumps/valves, the application of droplet-based microfluidics, paper-based microfluidic devices, and wireless networking capabilities for data transmission, are being explored.

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“…Creatinine, a byproduct of kidney function and a breakdown product of creatine phosphate in muscle, is produced at a constant rate in healthy individuals. Measuring serum creatinine is a simple test and is the most commonly used indicator of renal function through estimation of the glomerular filtration rate [258].…”

Section: Detection Of Metabolites and Small Moleculesmentioning

confidence: 99%