Point-of-care testing to promote cardiovascular disease risk assessment: A proof of concept study

Abstract

Updated cholesterol guidelines emphasize multivariable cardiovascular disease (CVD) risk estimation to guide treatment decision-making in primary prevention. This study tested the preliminary feasibility, acceptability and efficacy of point-of-care testing (POCT) and quantitative CVD risk assessment in high-risk adults to increase guideline-recommended statin use in primary prevention. Participants were aged 40–75 years, without CVD or diabetes mellitus, and potentially-eligible for consideration of statins based on estimated 10-year CVD risk from last-measured risk factor levels in the electronic health record. We performed POCT to facilitate quantitative CVD risk assessment with the Pooled Cohort Equations immediately before a scheduled primary care provider (PCP) visit. Outcomes were: physician documentation of a CVD risk discussion and statin prescription on the study date. We also assessed acceptability of the intervention through structured questionnaire. We recruited 18 participants (8 from an academic practice and 10 from a federally-qualified health clinic). After the intervention, 83% of participants discussed CVD risk with their PCP, 47% received a statin recommendation from their PCP, and 29% received a new statin prescription during the PCP visit. Participants reported high levels of satisfaction with the intervention. This study demonstrates that in initial testing pre-visit POCT and quantitative CVD risk assessment appears to be a feasible and acceptable intervention that may promote guideline-recommended statin initiation in primary prevention. Future research with an adequately powered trial is warranted to determine the effectiveness of this approach in clinical practice.

Diagnostic Accuracy of Cardiochek® Pa Point-of-care Testing (Poct) Analyser With a 3-in-1 Lipid Panel for Epidemiological Surveys

“…As a result, participants expressed a high level of satisfaction with the intervention. (27). A separate study aimed at assessing patient satisfaction with POCT in a general practice setting indicated that patients exhibited higher levels of satisfaction and con dence with this testing method.…”

Brazilian Lipid Cardiovascular Risk Pre and During the Covid 19 Pandemic in Asymptomatic and Severely Affected Groups

“…Besides all the medical information for each of the patients this database in full can be used for public health policies [13][14][15][16][17][18][19][20][21][22].…”

Novel Prediction Equations for Absolute Risk Assessment of Total Cardiovascular Disease Incorporating Cardiovascular-Kidney-Metabolic Health: A Scientific Statement From the American Heart Association

“…The 2013 ACC/AHA PCEs have been widely referenced in guidelines as detailed in the previous section, 21,24,28 validated extensively in external datasets, [31][32][33][34] and implemented broadly in clinical care. [35][36][37][38] With changing prevalence of risk factors (eg, tobacco use), secular trends in risk factor levels (eg, declines in lipid levels in the past decade 39,40 ), changes in care patterns (eg, more widespread use of various antihypertensive therapies), risk for incident ASCVD can be overestimated with the PCEs. 41 As a result, the CKM Health SAG agreed that it was now time to revise and update risk equations to address several key gaps in risk prediction with the PCEs and other existing models.…”