Point prevalence study of antimicrobial usage in acute care hospitals in the Slovak Republic

Štefkovičová, Mária; Litvová, S.; Melus, V; Krištúfková, Zuzana; Bražinová, Alexandra

doi:10.1016/j.jhin.2016.02.017

Cited by 7 publications

(5 citation statements)

References 16 publications

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“…Such a trend is a challenge to the hospitals surveyed and indicates that increasing efforts are needed from hospital staff. The finding that approximately one-third of patients were prescribed antimicrobials is consistent with previously published studies [2, 12–15].…”

Section: Discussionsupporting

confidence: 91%

Longitudinal point prevalence survey of antibacterial use in Northern Ireland using the European Surveillance of Antimicrobial Consumption (ESAC) PPS and Global-PPS tool

et al. 2018

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Antimicrobial resistance is a limiting factor for the success of the treatment of infectious diseases and is associated with increased morbidity and cost. The present study aims to evaluate prescribing patterns of antimicrobials and quantify progress in relation to targets for quality improvement in the prescription of antimicrobials in Northern Ireland's secondary care sector using three repetitive point prevalence surveys (PPS) over a 6-year period: the European Surveillance of Antimicrobial Consumption (ESAC-PPS) in 2009 and 2011 and the Global-PPS on Antimicrobial Consumption and Resistance in 2015. Out of 3605 patients surveyed over the three time points, 1239 (34.4%) were treated with an antibiotic, the most frequently prescribed antibiotic groups were a combination of penicillins, including β-lactamase inhibitors. Compliance with hospital antibiotic policies in 2009, 2011 and 2015 were 54.5%, 71.5% and 79.9%, respectively. Likewise, an indication for treatment was recorded in patient notes 88.5%, 87.7% and 90.6% in 2009, 2011 and 2015, respectively, and surgical prophylactic antibiotic prescriptions for >24 h was 3.9%, 3.2% and 0.7% in 2009, 2011 and 2015, respectively. Treatment based on biomarker data was used in 61.5% of cases. In conclusion, a general trend in the improvement of key antimicrobial-related quality indicators was noted. The PPS tool provided a convenient, inexpensive surveillance system of antimicrobial consumption and should be considered an essential component to establish and maintain informed antibiotic stewardship in hospitals.

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Section: Discussionsupporting

confidence: 91%

Longitudinal point prevalence survey of antibacterial use in Northern Ireland using the European Surveillance of Antimicrobial Consumption (ESAC) PPS and Global-PPS tool

et al. 2018

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“…1 Health care–associated infections (HAIs) is one important factor associated with AMR along with overuse of antibiotics. 2 Although control of HAIs is a normal practice in hospitals, it does not always receive enough attention until the AMR has deteriorated. The rapid development of a large number of invasive diagnoses and treatment technologies in recent years also brings challenges to infection control.…”

Section: Introductionmentioning

confidence: 99%

Estimating the Direct Medical Economic Burden of Health Care–Associated Infections in Public Tertiary Hospitals in Hubei Province, China

Liu

Cui

et al. 2017

Asia Pac J Public Health

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This study estimated the attributable direct medical economic burden of health care-associated infections (HAIs) in China. Data were extracted from hospitals' information systems. Inpatient cases with HAIs and non-HAIs were grouped by the propensity score matching (PSM) method. Attributable hospitalization expenditures and length of hospital stay were measured to estimate the direct medical economic burden of HAIs. STATA 12.0 was used to conduct descriptive analysis, bivariate χ test, paired Z test, PSM ( r = 0.25σ, nearest neighbor 1:1 matching), and logistic regress analysis. The statistically significant level was set at .05. The HAIs group had statistically significant higher expenditures and longer hospitalization stay than the non-HAIs group during 2013 to 2015 ( P < .001). The annual average HAI attributable total expenditure, medicines expenditure, out-of-pocket expenditure, and number of hospitalization days per inpatient were (2015 US$) 6173.02, 2257.98, and 1958.25 and 25 days during 2013 to 2015. The direct medical cost savings was estimated at more than 2015 US$12 billion per year in Chinese tertiary hospitals across the country. The significant attributable direct medical economic burden of HAIs calls for more effective HAI surveillance and better control with appropriate incentives.

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“…The point prevalence study of the use of antimicrobials agents is a useful surveillance method to obtain information on hospital epidemiology and has been widely used in several countries 15,16 . The present study is one of the first to investigate the use of antimicrobial agent drugs among older adult patients hospitalized in Brazil and showed a high prevalence in line with national and international studies.…”

Section: Resultsmentioning

confidence: 99%

“…The increased use of invasive procedures and devices and inadequate infection control practices are important transmission routes healthcare-related infections in hospitals and contribute to antimicrobial agent resistance 1 . Furthermore, the concern with infection leads to the early use of broad-spectrum empirical antimicrobial agent agents, which contributes to the development of multi-resistant microorganisms 1,16 . The pathogens identified in the study are classified as critical and high priority for the development and research of more effective antibiotic treatments 13 .…”

Section: Discussionmentioning

confidence: 99%

Antimicrobial therapy in older adults: profile of use and evaluation of the quality of prescription

Cruz¹,

Marçal²,

Reis³

et al. 2020

Rev Bras Farm Hosp Serv Saude

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Objectives: To analyze the point prevalence of antimicrobial agent use by older adults and to determine the quality of use in a teaching hospital. A pharmacoepidemiological, observational study. Methods: Retrospective collection of clinical, microbiological and pharmacotherapeutic data in medical records. Inclusion criteria: age ≥ 60 years old, in use of one or more antimicrobial agents. The resistant microorganisms classified as priority pathogens by the World Health Organization (WHO) were identified. The quality of antimicrobial agent use according to quality indicators described by Van den Bosch et al. (2015) was determined. A descriptive statistical analysis was performed. Results: Of the 130 hospitalized older adult individuals, 40.8% were using one or more antimicrobials agents on the day of point prevalence. Among the 50 resistant microorganisms identified in the cultures, 54.0% corresponded to pathogens of critical priority. Antibiotic glycopeptides (14.9%) and penicillins associated with beta-lactamase inhibitors (13.8%) were the most prescribed classes of antimicrobial agents. The Quality Indicators (QIs) of antimicrobial therapy demonstrated more frequent inadequacy regarding therapeutic monitoring, sequential therapy and blood culture request. Conclusions: The prevalence of antimicrobial agent use in older adults was high. Empirical therapy is often developed in line with that advocated by the Infection Control Commission. The high isolation of critical pathogens according to the WHO, evidences the importance of actions to ensure the rational use of drugs in the institution. The QIs demonstrated the need to implement guidelines for systematizing therapeutic antimicrobial agent monitoring in the institution and educational action on the process of requesting blood cultures.

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Point prevalence study of antimicrobial usage in acute care hospitals in the Slovak Republic

Cited by 7 publications

References 16 publications

Longitudinal point prevalence survey of antibacterial use in Northern Ireland using the European Surveillance of Antimicrobial Consumption (ESAC) PPS and Global-PPS tool

Longitudinal point prevalence survey of antibacterial use in Northern Ireland using the European Surveillance of Antimicrobial Consumption (ESAC) PPS and Global-PPS tool

Estimating the Direct Medical Economic Burden of Health Care–Associated Infections in Public Tertiary Hospitals in Hubei Province, China

Antimicrobial therapy in older adults: profile of use and evaluation of the quality of prescription

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