Point prevalence survey of antibiotic use and healthcare-associated infections in acute care hospitals: a comprehensive report from the Marche Region of Italy

Barbadoro, P.; Dolcini, J.; Fortunato, C.; Mengarelli detto Rinaldini, D.; Martini, E.; Gioia, M.G.; Mengoni, D.; D'Errico, M.M.; Schimizzi, A.M.; Baldassarri, A.; Vincitorio, D.; Biondi, M.; Ferretti, P.; Maestri, S.; Draghi, E.; Arsego, D.; Ferrara, L.; Vittorio, M.; Capasso, M.; Di Falco, C.; Scaloni, G.; Di Febbo, M.; Aguzzi, A.; Benigni, V.; Tavio, M.; Marigliano, A.; Rinaldi, A.; Marcello, A.; Mazzacchera, A.; Serafini, A.; Genga, A.; Giorgio Mangino, C.D.; Vesprini, C.; Barbaresi, D.; Scutti, D.; Mali, E.; Semprini, G.M.; Marchini, G.; Ricciotti, G.M.; Mercante, G.; Paolorossi, G.; Faggi, M.I.; Gatti, L.; Uncini, M.; Toscano, O.D.; Sabatini, P.; Rosati, S.; Bizzarri, S.; Poggioli, T.; Garota, I.; Pertosa, M.E.; Mazzoccanti, M.R.

doi:10.1016/j.jhin.2023.07.025

Journal of Hospital Infection

2023

DOI: 10.1016/j.jhin.2023.07.025

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Point prevalence survey of antibiotic use and healthcare-associated infections in acute care hospitals: a comprehensive report from the Marche Region of Italy

P. Barbadoro,

J. Dolcini,

C. Fortunato

et al.

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2024

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Cited by 3 publications

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Impact of COVID-19 on healthcare-associated infections and antimicrobial use in Italy, 2022

Vicentini,

Russotto,

Bussolino

et al. 2024

Journal of Hospital Infection

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Impact of COVID-19 on healthcare-associated infections and antimicrobial use in Italy, 2022

Vicentini,

Russotto,

Bussolino

et al. 2024

Journal of Hospital Infection

View full text Add to dashboard Cite

Antibiotic use and adherence to the WHO AWaRe guidelines across 16 hospitals in Zambia: a point prevalence survey

Chizimu,

Mudenda,

Yamba

et al. 2024

JAC-Antimicrobial Resistance

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Background The inappropriate use of antibiotics in hospitals contributes to the development and spread of antimicrobial resistance (AMR). This study evaluated the prevalence of antibiotic use and adherence to the World Health Organization (WHO) Access, Watch and Reserve (AWaRe) classification of antibiotics across 16 hospitals in Zambia. Methods A descriptive, cross-sectional study employing the WHO Point Prevalence Survey (PPS) methodology and WHO AWaRe classification of antibiotics was conducted among inpatients across 16 hospitals in December 2023, Zambia. Data analysis was performed using STATA version 17.0. Results Of the 1296 inpatients surveyed in the 16 hospitals, 56% were female, and 54% were aged between 16 and 50 years. The overall prevalence of antibiotic use was 70%. Additionally, 52% of the inpatients received Watch group antibiotics, with ceftriaxone being the most prescribed antibiotic. Slightly below half (48%) of the inpatients received Access group antibiotics. Compliance with the local treatment guidelines was 53%. Conclusions This study found a high prevalence of prescribing and use of antibiotics in hospitalized patients across the surveyed hospitals in Zambia. The high use of Watch group antibiotics was above the recommended threshold indicating non-adherence to the WHO AWaRe guidelines for antibiotic use. Hence, there is a need to establish and strengthen antimicrobial stewardship programmes that promote the rational use of antibiotics in hospitals in Zambia.

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Hospital Context Determinants of Variability in Healthcare-Associated Infection Prevalence: Multi-Level Analysis

Malheiro,

Gomes,

Fernandes

et al. 2024

Microorganisms

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Healthcare-associated infections (HAIs) represent a major challenge in patient safety that affects services disproportionally. This paper aimed to assess how the HAI prevalence varies between hospital services and what contextual characteristics may explain such variance. A cross-sectional study was conducted on adult patients in Portuguese hospitals, using data from the European point prevalence survey of HAI prevalence. The study variables included patient, structural, and process variables, tested as risk factors, with patients clustered in hospitals. Variables with a p-value ≤ 0.2 in univariate analyses were retested in a multivariable model. A total of 18,261 patients from 119 hospitals were included: 736 from 56 intensive care units (ICUs), 3160 from 72 surgical departments, and 8081 from 90 medical departments. The HAI prevalence was 7.9%, 5.9%, and 1.7%, respectively. In ICUs, only the number of devices was associated with the HAI prevalence. In surgical departments, age, comorbidities, being a specialized hospital, and a higher ratio of infection prevention and control (IPC) personnel were associated with higher SSI. The safety climate was associated with lower SSI. In medical departments, age and devices were positively associated, whereas a larger ratio of IPC nurses was negatively associated. These results may help implement targeted interventions to achieve optimal results in each department.

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Point prevalence survey of antibiotic use and healthcare-associated infections in acute care hospitals: a comprehensive report from the Marche Region of Italy

Cited by 3 publications

References 18 publications

Impact of COVID-19 on healthcare-associated infections and antimicrobial use in Italy, 2022

Impact of COVID-19 on healthcare-associated infections and antimicrobial use in Italy, 2022

Antibiotic use and adherence to the WHO AWaRe guidelines across 16 hospitals in Zambia: a point prevalence survey

Hospital Context Determinants of Variability in Healthcare-Associated Infection Prevalence: Multi-Level Analysis

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