A B S T R A C TWe characterize the seismic response of Lake Vostok, an Antarctic subglacial lake located at nearly 4 km depth below the ice sheet. This study is relevant for the determination of the location and morphology of subglacial lakes. The characterization requires the design of a methodology based on rock physics and numerical modelling of wave propagation. The methodology involves rock-physics models of the shallow layer (firn), the ice sheet and the lake sediments, numerical simulation of synthetic seismograms, ray tracing, τ -p transforms, and AVA analysis, based on the theoretical reflection coefficients. The modelled reflection seismograms show a set of straight events (refractions through the firn and top-ice layer) and the two reflection events associated with the top and bottom of the lake. Theoretical AVA analysis of these reflections indicates that, at near offsets, the PP-wave anomaly is negative for the ice/water interface and constant for the water/sediment interface. This behaviour is shown by AVA analysis of the synthetic data set. This study shows that subglacial lakes can be identified by using seismic methods. Moreover, the methodology provides a tool for designing suitable seismic surveys.