Poisoning due to household products: A ten years retrospective analysis of telephone calls to the National Poisons Information Centre, All India Institute of Medical Sciences, New Delhi, India

Peshin, Sharda Shah; Gupta, Yogendra Kumar

doi:10.1016/j.jflm.2018.07.005

Cited by 28 publications

(45 citation statements)

References 42 publications

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“…Poisoning due to the use of detergents, household products, and chemicals have also been reported in several studies [26,[28][29][30]. The leading cause of this poisoning in all of these studies is the storage of these products in the bottles of beverages, mixing these materials with foods, and the misuse of these products in kitchen utensils.…”

Section: Discussionmentioning

confidence: 92%

Investigating Suicide Rate and Poisoning Severity and Their Relationship With Birth Month

Dorooshi

Shariat

Shirvani

et al. 2019

Int J Med Toxicol Forensic Med

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Background: One of the most frequent causes of death is poisoning worldwide. Investigating the causes of mortality due to poisoning profoundly affects making decisions and improving standards for preventing adverse events. Therefore, to better understand this problem and evaluate the causes, this study aimed to determine the risk of suicide using the SAD PERSONS Scale (SPS) criteria and its relationship with the birth month in poisoned patients.Methods: This cross-sectional descriptive-analytic study was conducted on poisoned patients admitted to Khorshid Hospital in Isfahan City, Iran, in 2018. First, the patients’ age, gender, and birth month were recorded. Then, their suicide risk was assessed by SPS.Results: From 2735 referred patients with poisoning, 1839 (67.2%) attempted suicide, and 896(32.8%) cases were poisoned. The Mean±SD SPS score in patients with suicidal attempts was 4.89±1.94, and in the poisoned patients was equal to 2.74±1.46 (P<0.001). There was no significant relationship between suicide and birth month; however, gender (male), age, depression, previous suicidal attempts, ethanol abuse, rational thinking loss, social support lacking, and being unmarried significantly increased the risk of suicide (P<0.01). In addition, the SPS scores ≥5 with a sensitivity of 43.77%, and specificity of 98.44% had an acceptable diagnostic value in identifying the risk of suicide (P<0.0001).Conclusion: As SPS criteria have an appropriate diagnostic value for suicide prediction, it is recommended that these criteria be assessed among individuals with susceptible suicide characteristics (e.g. males, elders, depression, the lack of social support, etc.), to prevent future suicide attempts and appropriate medical-psychological measures.

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Section: Discussionmentioning

confidence: 92%

Investigating Suicide Rate and Poisoning Severity and Their Relationship With Birth Month

Dorooshi

Shariat

Shirvani

et al. 2019

Int J Med Toxicol Forensic Med

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“…Other authors commented the increase in household product exposures observed in many developed countries arguing that the probable reason for the high incidence detected could be ascribed to careless storage, ignorance, non-compliance with prescribed instructions for use and negligible parental supervision in case of children [24]. In the European Union a survey highlighted that the 70% of European citizens use the label to obtain information about the potential danger of a chemical, although chemical hazard pictograms are usually not very understood [25].…”

Section: Discussionmentioning

confidence: 99%

Significant variations of dangerous exposures during COVID-19 pandemic in Italy: a possible association with the containment measures implemented to reduce the virus transmission

Giordano

Petrolini

Spagnolo

et al. 2021

Preprint

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Background: In response to the COVID-19 health emergency, mass media widely spread guidelines to stop the virus transmission, leading to an excessive and unaware use of detergents and disinfectants. In Italy and in other countries this tendency caused a significant increase of exposures to these products in 2020. Evaluating data collected by the Italian Pavia Poison Centre (PPC), this study intends to examine the relationship between the COVID-19 lockdown and the variations of exposures to specific product categories possibly associated to the containment measures implemented.Simultaneously, this work shows the effectiveness of the European Products Categorisation System (EuPCS) in surveillance activities of dangerous chemicals.Methods: Exposure cases managed by the PPC during March-May 2020 (lockdown) and during the same months of 2017-2018-2019 were compared. Differences in categorical variables were tested with the Chi-square test. The level of significance was set at Alpha = 0.05. The study included all EuPCS groups but specifically focused on cleaners, detergents, biocides and cosmetics. Results: During the lockdown calls from private citizens significantly increased (+11.5%, p<0.001) and occupational exposures decreased (-11.7%, p<0.05). Among Cleaners, exposures to Bleaches slightly increased while Drain cleaning products went through a significant reduction (-13.9%, p<0.05). An increase of exposures to Disinfectants was observed (+7.7%, p<0.01), particularly to those for surfaces (+6.8%, p<0.05). Regarding Cosmetics, both handwashing soaps and gel products significantly increased (respectively: +25.0 and +9.7%, p<0.05).Among children 1-5 years, the statistical significance is reached with exposures to Dishwashing detergents (+13.1%), handwashing soaps (+28.6%, p<0.05) and handwashing gel products (+16.8%, p=0.01). Contrarily, Liquid Laundry Detergent Capsules significantly decreased (-25%; p=0.001). The general severity of exposures decreased (Moderate: -10.1%, p<0.001). Conclusions: This study investigated the relationship between the COVID-19 lockdown and the variations of exposures to some product categories related to the containment measures. The results obtained support any action to be taken by Competent Authorities to implement measures for a safer use of cleaners/disinfectants. This paper shows the benefit in applying the EuPCS to categorize products according to their intended use, though an extension of this system to products not covered by CLP Regulation may be a further advantage.

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“…The rampant use of mosquito repellants are of a serious concern for health and the environment 20 , and their easy availability and widespread use are responsible for frequent poisoning. 21 It has been reported that exposure to pesticides is associated with increased risk of degenerative as well as various other pathological disorders. 22,23 Oxidative stress plays a crucial role in the development of several diseases such as atherosclerosis, cancer, diabetics, rheumatoid arthritis, myocardial infarction, autoimmune disease, and aging.…”

Section: Discussionmentioning

confidence: 99%

“…The rampant use of mosquito repellants are of a serious concern for health and the environment, and their easy availability and widespread use are responsible for frequent poisoning . It has been reported that exposure to pesticides is associated with increased risk of degenerative as well as various other pathological disorders .…”

Section: Discussionmentioning

confidence: 99%

Oxidative stress and neuromodulatory effects of deltamethrin and its combination with insect repellents in rats

Magesh

Anitha

Vijayaraghavan

et al. 2019

Environmental Toxicology

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Deltamethrin (DEL) and other synthetic repellents like N,N‐diethyl benzamide (DEB), N,N‐diethyl phenylacetamide (DEPA), and N,N‐diethyl meta toluamide (DEET) are widely used due their high efficacy against mosquitoes. We evaluated the safe dose on exposure to insecticide and insect repellent individually and in combination in Wistar rats. Rats were administrated with individual chemicals DEL, DEB, DEPA, and DEET and in combination of DEL along DEB, DEPA, and DEET. The reduced glutathione and its detoxifying enzymes were significantly increased in DEL treated rats. Serotonin, dopamine, and noradrenaline were increased in DEL alone and its combination groups. Histopathology revealed that DEL and along with other insect repellants can cause lung toxicities. This study suggests that DEL in combination with other insect repellents showed antagonistic effect against oxidative stress, and there was no significant toxicological effect in the combination groups. The insect repellents with DEL cause less toxic effect and is safe for use.

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Poisoning due to household products: A ten years retrospective analysis of telephone calls to the National Poisons Information Centre, All India Institute of Medical Sciences, New Delhi, India

Cited by 28 publications

References 42 publications

Investigating Suicide Rate and Poisoning Severity and Their Relationship With Birth Month

Investigating Suicide Rate and Poisoning Severity and Their Relationship With Birth Month

Significant variations of dangerous exposures during COVID-19 pandemic in Italy: a possible association with the containment measures implemented to reduce the virus transmission

Oxidative stress and neuromodulatory effects of deltamethrin and its combination with insect repellents in rats

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