Poisoning hospitalization correlates with poison center call frequency

Albertson, Timothy E; Tharratt, R. Steven; Marquardt, Kathy; Alsop, Judith A.; Ninomiya, John K.; Foulke, Garrett E.

doi:10.1007/bf03161193

Cited by 2 publications

(1 citation statement)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Data from a statewide database of hospital admissions demonstrated a 3-day shorter hospital LOS for overdose patients who received poison center consultations versus those who did not [21]. Another, recent study comparing poison center call volumes and hospital LOS was unable to identify any such correlation [22]. Two past studies examine the effects of hospital medical toxicology services on resource utilization.…”

Section: Discussionmentioning

confidence: 98%

The Clinical Management of Acetaminophen Poisoning in a Community Hospital System: Factors Associated with Hospital Length of Stay

Offerman

2010

J. Med. Toxicol.

View full text Add to dashboard Cite

Acetaminophen (APAP) overdose is the most common pharmaceutical poisoning. The objective of this study was to examine the management of patients admitted for treatment of APAP overdose. Factors impacting hospital length of stay (LOS) were of particular interest. This was a retrospective cohort study of patients admitted to Kaiser Permanente Northern California hospitals for APAP overdose from July 2003 through December 2007. Medical records were abstracted for patient demographic data, key factors of overdose, California Poison Control System (CPCS) contact, data regarding hospital course, transfer for liver transplantation, and death. Four hundred thirty-five patients were included. The mean hospital LOS was 66.5 h (95% CI 62.1, 71.0). Four patients (0.9%) died. Eight patients (1.8%) were transferred for liver transplantation, but all of these patients later recovered without transplant. Of 289 cases eligible for placement on the RumackMatthew nomogram (acute ingestion with known time of ingestion <24 h and normal liver enzymes), 161 (55.7%) had APAP levels above the "200" line and 77 (26.6%) fell below the "150" line. CPCS was contacted in 295 cases (67.8%). Mean LOS in cases with CPCS consultation was 61.9 h (95% CI 57.2, 66.5 h) versus 76.3 h (95% CI 66.6, 86.0 h) in those without. LOS in cases treated with IV NAC was 67.1 h (95% CI 57.7, 76.5 h) versus 66.4 h (95% CI 61.2, 71.5 h) in cases treated with oral NAC. Many patients admitted for APAP overdose had serum APAP levels below the minimum toxicity level. Use of IV NAC did not impact hospital LOS. CPCS consultation appeared to decrease mean hospital LOS.

show abstract

Section: Discussionmentioning

confidence: 98%

The Clinical Management of Acetaminophen Poisoning in a Community Hospital System: Factors Associated with Hospital Length of Stay

Offerman

2010

J. Med. Toxicol.

View full text Add to dashboard Cite

show abstract

Acute intoxications: Differences in management between six Dutch hospitals

Duineveld

Vroegop

Schouren

et al. 2012

Clinical Toxicology

View full text Add to dashboard Cite

Context . Acute intoxications are frequently seen in Dutch hospitals. Based on single-centre studies and the fact that there are no clear guidelines, we hypothesised that hospital admission of acute intoxications may vary. Furthermore, decontamination treatment of poisonings may differ between hospitals, as earlier studies showed that adherence to international guidelines concerning decontamination may be poor. Objective . We aim to identify possible variations in Dutch hospital admission and decontamination treatment of patients with acute intoxications. Materials and methods . Data on acute intoxications was retrospectively collected from patient records from the emergency departments of six Dutch hospitals. All patients older than 14 years who presented between 1 January 2008 and 31 December 2008 were included in the study. Results . The percentage of suicide attempts differed signifi cantly between the hospitals (25 -73%, p Ͻ 0.0001) as equally the percentage of intoxications with drugs of abuse (18 -61%, p Ͻ 0.0001). Marked differences in admission rates were found (27 -78%, p Ͻ 0.0001) and these differences remained even when intoxications because of suicide attempts and drugs of abuse were analysed separately (admission rate of 52 -87%, p Ͻ 0.0001 and 8 -71%, p Ͻ 0.0001 respectively). Reported consultation with the National Poisons Information Centre differed between hospitals (range 0% to 80 -100%). No statistical differences were found between hospitals for the use of activated charcoal (16.1 -42.5%, p = 0.037). Gastric lavage was used infrequently in all hospitals. (6.6 -16.7%, p = 0.614). Discussion and conclusion . The admission rate of patients with an acute intoxication varies considerably, especially in the case of intoxications with drugs of abuse. Consultations with the National Poisons Information Centre differed between the six hospitals. Rates of decontamination did not vary, which may indicate adherence to guidelines by the American Academy of Clinical Toxicology, European Association of Poisons Centres and Clinical Toxicologists. National guidelines or admission algorithms may reduce variations in poisoning management and make the care for these patients more effi cient.

show abstract

Poisoning hospitalization correlates with poison center call frequency

Cited by 2 publications

References 27 publications

The Clinical Management of Acetaminophen Poisoning in a Community Hospital System: Factors Associated with Hospital Length of Stay

The Clinical Management of Acetaminophen Poisoning in a Community Hospital System: Factors Associated with Hospital Length of Stay

Acute intoxications: Differences in management between six Dutch hospitals

Contact Info

Product

Resources

About