Pol-CDRIE registry – 1-year observational data on patients hospitalized due to cardiac device-related infective endocarditis in Polish referential cardiology centres

Abstract

BACKGROUND The rate of cardiac device-related infective endocarditis (CDRIE) is increasing worldwide, but no detailed data are available for Poland. AIMS We aimed to evaluate clinical, diagnostic, and therapeutic data of patients hospitalized due to CDRIE in 22 Polish referential cardiology centers from May 1, 2016 to May 1, 2017. METHODS Participating cardiology departments were asked to fill in a questionnaire that included data on the number of hospitalized patients, number and types of implanted cardiac electrotherapy devices, and number of infective endocarditis cases. We also collected clinical data and data regarding the management of patients with CDRIE. RESULTS Overall, 99 621 hospitalizations were reported. Infective endocarditis unrelated to cardiac device was the cause of 596 admissions (0.6%), and CDRIE, of 195 (0.2%). Pacemaker was implanted in 91 patients with CDRIE (47%); cardioverter-defibrillator, in 51 (26%); cardiac resynchronization therapy

Native valve, prosthetic valve, and cardiac device-related infective endocarditis: A review and update on current innovative diagnostic and therapeutic strategies

“…Further, results of blood cultures can be inconclusive due to contamination by commensal bacteria, a complex polymicrobial biofilm (Oberbach et al, 2017), or insufficient amounts of bacteria to culture. Negative blood cultures are found in approximately 24% of all IE cases, which is similar for NVE (25%), CDRIE (26%), and PVE (23%) (Hussein et al, 2016;Koneru et al, 2018;Calais et al, 2019;de Camargo et al, 2019;El Gabry et al, 2019;Habib et al, 2019;Heriot et al, 2019;Nesterovics et al, 2019;Płońska-Gościniak et al, 2019;San et al, 2019;Witten et al, 2019;Bohbot et al, 2021;Duval et al, 2021;Jędrzejczyk-Patej et al, 2021;Michałowska et al, 2021;Pyo et al, 2021).…”

“…Coagulase-negative staphylococci have a prevalence of 6.3% in NVE, which is in contrast to CDRIE with 25.2% ( Hussein et al, 2016 ; Koneru et al, 2018 ; Calais et al, 2019 ; Habib et al, 2019 ; Nesterovics et al, 2019 ; San et al, 2019 ; Witten et al, 2019 ; Bohbot et al, 2021 ; Duval et al, 2021 ; Pyo et al, 2021 ). Microorganisms obtained from cultures of CDRIE patients were predominately staphylococci (54%), followed by streptococci (12%) and enterococci (5%) ( Habib et al, 2015 ; Hussein et al, 2016 ; Koneru et al, 2018 ; Calais et al, 2019 ; Nesterovics et al, 2019 ; Płońska-Gościniak et al, 2019 ; Witten et al, 2019 ; Jędrzejczyk-Patej et al, 2021 ). Staphylococci are considerably more prevalent in CDRIE compared to NVE (27%) and PVE (32%) ( Hussein et al, 2016 ; Koneru et al, 2018 ; Calais et al, 2019 ; de Camargo et al, 2019 ; El Gabry et al, 2019 ; Habib et al, 2019 ; Heriot et al, 2019 ; Nesterovics et al, 2019 ; Płońska-Gościniak et al, 2019 ; San et al, 2019 ; Witten et al, 2019 ; Bohbot et al, 2021 ; Duval et al, 2021 ; Jędrzejczyk-Patej et al, 2021 ; Michałowska et al, 2021 ; Pyo et al, 2021 ).…”

Predictors of Long-Term Infections After Cardiac Implantable Electronic Device Surgery ― Utility of Novel PADIT and PACE DRAP Scores ―

“…Prior studies identified hematoma with an Previous studies report that the risk of CDI is the highest for CRT procedures (1.1-4.8%) followed by ICD (0.7-3.3%) and pacemaker surgery (0.5-1.19%). 4,5,7 The increased rate of CRT device infections is associated with advanced device complexity and time-consuming procedure, but also patient multimorbidity is of great importance. 20 In our study population, all ICD and CRT procedures were performed by experienced operators with a high annual number of procedures, which probably influenced the lower CDI frequency.…”

“…1,2 The reported CDI occurrence varies between 0.68% and 2.2% of CIED procedures, with significantly higher CDI incidence for implantable cardioverter-defibrillator (ICD) or cardiac resynchronization therapy (CRT) procedures (up to 4.8%). [2][3][4][5] Previous studies report several patient-related and procedure-related risk factors for CDI development, but many of them were retrospective analyses with inconsistent CDI definitions. 4,6,7 Moreover, only a few of the previous reports focus on ICD or CRT recipients particularly.…”

Nuclear cardiology: an overview of radioisotope techniques used in the diagnostic workup of cardiovascular disorders

“…Also 18 F -FDG-PET does not differentiate thrombi, soft atherosclerotic plaque, primary cardiac tumors, postoperative inflammatory infiltrates, and reaction to a foreign body. 4, 42,43 Some of the disadvantages of scintigraphy with labeled leukocytes compared with PET/CT are the lower spatial resolution and its limited value in nonbacterial infections (the majority of leukocytes labeled are neutrophils). 43 implantable electronic devices (CIEDs).…”