Polarity, resistivity and biocompatibility of polyethylene doped with carbon black

Švorčı́k, Václav; Rybka, V.; Hnatowicz, V.; Bačáková, Lucie

doi:10.1007/bf00270988

Cited by 25 publications

(11 citation statements)

References 8 publications

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“…Given equal energy, lighter ions have a higher mean distance range of penetration into the polymer in comparison to heavier ones, which are implanted closer to the surface of the modified substrate. Since ions always penetrate deeper than the uppermost surface layer regardless of weight and energy, it is a safe assumption the adhesion of cells is dependent not only on the very surface of the polymer but also on the physico-chemical properties of a certain depth range of the surface layers [57]. …”

Section: Ion Implantationmentioning

confidence: 99%

Surface Modification of Polymer Substrates for Biomedical Applications

2017

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While polymers are widely utilized materials in the biomedical industry, they are rarely used in an unmodified state. Some kind of a surface treatment is often necessary to achieve properties suitable for specific applications. There are multiple methods of surface treatment, each with their own pros and cons, such as plasma and laser treatment, UV lamp modification, etching, grafting, metallization, ion sputtering and others. An appropriate treatment can change the physico-chemical properties of the surface of a polymer in a way that makes it attractive for a variety of biological compounds, or, on the contrary, makes the polymer exhibit antibacterial or cytotoxic properties, thus making the polymer usable in a variety of biomedical applications. This review examines four popular methods of polymer surface modification: laser treatment, ion implantation, plasma treatment and nanoparticle grafting. Surface treatment-induced changes of the physico-chemical properties, morphology, chemical composition and biocompatibility of a variety of polymer substrates are studied. Relevant biological methods are used to determine the influence of various surface treatments and grafting processes on the biocompatibility of the new surfaces—mammalian cell adhesion and proliferation is studied as well as other potential applications of the surface-treated polymer substrates in the biomedical industry.

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Section: Ion Implantationmentioning

confidence: 99%

Surface Modification of Polymer Substrates for Biomedical Applications

2017

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“…Different procedures have been used to prepare carbon-polymer composites for this specific application. Improving of biocompatibility of polymers doped, e.g., with carbon black [1] or carbon fibers [2] was studied. It was also found that the cell adhesion and proliferation could be affected by carbonization of polymer surface layer by pyrolysis [3], ion implantation [4,5] or by UV-irradiation [6] and by exposure to plasma discharge [7].…”

Section: Introductionmentioning

confidence: 99%

Characterization and cytocompatibility of carbon layers prepared by photo-induced chemical vapor deposition

et al. 2007

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“…These cells earlier had been found to respond very sensitively to environmental conditions, including in vitro changes in the physicochemical surface properties of polymeric growth supports modified by ion implantation and chemical doping. 34,35 Cells with vascular smooth muscle cell phenotype, determined by expression of alpha-actin, metavinculin, hcaldesmon, smooth muscle myosin heavy chains, and calponin are present not only in the bone vasculature but also in bone marrow and endosteal cell layer lining bone trabeculae; 36 thus they can enter into direct contact with implanted artificial material. In addition, these cells are capable of osteoblast-like differentiation and production of mineralized bone matrix 37,38 and can participate in osteogenesis.…”

Section: Introductionmentioning

confidence: 99%

Polishing and coating carbon fiber‐reinforced carbon composites with a carbon‐titanium layer enhances adhesion and growth of osteoblast‐like MG63 cells and vascular smooth muscle cells in vitro

Bačáková¹,

Starý²,

Kofroňová³

et al. 2001

J. Biomed. Mater. Res.

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Carbon fiber-reinforced carbon composites (CFRC) are considered to be promising materials for orthopedic and dental surgery. Their mechanical properties can be tailored to be similar to those of bone, and their chemical composition (close to pure carbon) promises that they will be tolerated well by the surrounding tissue. In this study, CFRC composites were fabricated from phenolic resin and unidirectionally oriented Torayca carbon fibers by carbonization (1000°C) and graphitization (2500°C). The material then was cut with a diamond saw into sheets of 8 × 10 × 3 mm, and the upper surface was polished by colloidal SiO 2 and/or covered with a carbon-titanium (C:Ti) layer (3.3 m) using the plasma-enhanced physical vapor deposition method. Three different kinds of modified samples were prepared: polished only, covered only, and polished + covered. Untreated samples served as a control. The surface roughness of these samples, measured by a Talysurf profilometer, decreased significantly after polishing but usually did not decrease after coating with a C:Ti layer. On all three modified surfaces, human osteoblast-like cells of the MG63 line and rat vascular smooth muscle cells (both cultured in a Dulbecco's minimum essential medium with 10% fetal bo-vine serum) adhered at higher numbers (by 21-87% on day 1 after seeding) and exhibited a shorter population doubling time (by 13-40%). On day 4 after seeding, these cells attained higher population densities (by 61-378%), volume (by 18-37%), and protein content (by 16-120%). These results were more pronounced in VSMC than in MG63 cells and in both groups of C:Ti-covered samples than in the polished only samples. The release of carbon particles from the CFRC composites was significantly decreased-by 8 times in the polished only, 24 times in the covered only, and 42 times in the polished + covered samples. These results show that both polishing and carbon-titanium covering significantly improve the biocompatibility of CFRC composites in vitro, especially when these two modifications are combined.

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Polarity, resistivity and biocompatibility of polyethylene doped with carbon black

Cited by 25 publications

References 8 publications

Surface Modification of Polymer Substrates for Biomedical Applications

Surface Modification of Polymer Substrates for Biomedical Applications

Characterization and cytocompatibility of carbon layers prepared by photo-induced chemical vapor deposition

Polishing and coating carbon fiber‐reinforced carbon composites with a carbon‐titanium layer enhances adhesion and growth of osteoblast‐like MG63 cells and vascular smooth muscle cells in vitro

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